… of melanotic Plasmodium spp. capsules in mosquitoes reveal eumelanin-pheomelanin composition and identify AgMesh as a modulator of parasite infection

E Camacho, Y Dong, Y Anglero-Rodriguez, D Smith… - bioRxiv, 2021 - biorxiv.org
… The melanin biosynthesis pathway involves a multistep … accelerate melanin precursor
polymerization, anchor melanin, … fungus Cryptococcus neoformans as a model to study melanin

Neutrophil-mediated antifungal activity against highly virulent Cryptococcus gattii strain R265

K Ueno, N Yanagihara, Y Otani, K Shimizu… - Medical …, 2019 - academic.oup.com
Cryptococcus gattii and Cryptococcus neoformans are … Sample preparation and immunoblotting
analysis were … polymerization (Fig. 3A, 3B). We also found that neutrophils engulfed …

[HTML][HTML] Talaromyces marneffei Infection: Virulence Factors and Rapid Diagnostics

S Youngchim - Infectious Diseases Annual Volume 2022, 2022 - intechopen.com
… The DHN melanin biosynthesis gene cluster of T. marneffei was studied [… that can polymerize
to form DOPA melanin (Figure 6). … and inflammatory response in mice infected with the MP1 …

Conidial melanin of the human-pathogenic fungus Aspergillus fumigatus disrupts cell autonomous defenses in amoebae

I Ferling, JD Dunn, A Ferling, T Soldati, F Hillmann - MBio, 2020 - Am Soc Microbiol
… protective antifungal immunity of both mice and humans (3). … in 1,8-DHN-melanin biosynthesis;
ΔrodA, ΔrodB, and ΔrodA … Synthetic melanin was polymerized spontaneously from 1,8-…

Replicative aging remodels the cell wall and is associated with increased intracellular trafficking in human pathogenic yeasts

VKA Silva, S Bhattacharya, NK Oliveira, AG Savitt… - MBio, 2022 - Am Soc Microbiol
… upregulate genes of cell wall biosynthesis, leading to cell wall … IMPORTANCE Cryptococcus
neoformans and Candida … with Spurr resin, and polymerized in an oven at 60C for 24 h. …

Targeting virulence factors as an antimicrobial approach: pigment inhibitors

S Ni, B Li, Y Xu, F Mao, X Li, L Lan… - Medicinal Research …, 2020 - Wiley Online Library
neoformans in particular, which is synthesized as an … on the production of melanin in
Cryptococcus neoformans H99 cells. The … of hematin polymerization based on the detection of 14 …

[HTML][HTML] Radioimmunotherapy as a pathogen-agnostic treatment method for opportunistic mucormycosis infections

…, ME Malo, KJH Allen, C Frank… - Access …, 2023 - microbiologyresearch.org
… Using Cryptococcus neoformans and Candida albicans as model organisms in vitro and …
Synthesis of polymerized melanin by Cryptococcus neoformans in infected rodents. …

[PDF][PDF] Melanin: progress, prospects, and challenges in synthesis and commercial applications

S Pandey, R Shahwal, A Sur - 2023 - academia.edu
… will oxidize and autopolymerized to form melanin due to its … fungus that forms melanin are
as follows: Cryptococcus neoformans, … (isolated from the fungus Gliocephalotrichum) in mice

Multidisciplinary characterization of melanin pigments from the black fungus Cryomyces antarcticus

C Pacelli, A Cassaro, A Maturilli, AM Timperio… - Applied Microbiology …, 2020 - Springer
… There are several melanin types based on different polymerization as the brown-black …
standard melanins, chemically synthesized by oxidation of DOPA and DHN-melanin. NaOH was …

Melanin biopolymers from microbial world with future perspectives—A review

…, N Karthikeyan, C Ramesh Kumar - Archives of …, 2023 - Springer
… The ability of several microbes to synthesize melanin, … auto-polymerize to produce melanin
called DOPA-melanin or … be produced by the fungus Cryptococcus neoformans, also other …