… 2 , guaranteeing the survival and function of antitumor immune cells. When modified with
anti-CD3/… tumor homing ability and antitumor immune response by activating DCs and CD8 + T-…

… CD4 + T cells have direct roles in anti-tumor and anti-viral … , can elicit robust specific CD4 +
T cell responses in vitro (96, 97). … of Th cells is more adapted to mediate a protective response …

… , these cellular attributes characterize T cells with antitumor … − [(target cell number in the
presence of effector cells)/(target … T-cell persistence in vivo and durability of ACT responses (51…

… limitations, including the use of synthetic particles (3, 18); … , complete protection against
rechallenge with MC38 cells on day … eTAT elicited a robust Ag-specific CD8+ T-cell response not …

… antigen-presenting cells (APCs), priming of CD4 + or CD8 + … and cross-presented to
elicit cytotoxic T lymphocytes (CTLs). [ … (HPLC) confirmed the successful synthesis of 2′3′-cGAMP …

… vaccines alone can elicit a broad immune response, their … in studies that can promote CD4
+ T cell expansion and increase … + T cells in the antitumor efficacy of the combination therapy, …

… There is also variation depending on the T cell activation … less efficient than cell based
artificial antigen presenting cells (… targeted for eliciting an antigen-specific T cell response. These …

… , which are essential for antiviral and anticancer therapies. … an aim to induce protective immune
responses by targeting DCs. For … Considering both safety and efficiency, various synthetic …

… to antigen-presenting cells (APCs), the primary mediators of … design of novel APC-targeted
therapeutic interventions for ex … coculture studies using PMEL T cells, synthesis and 1 H NMR …

… tumor cells into artificial antigen-presenting cells (aAPCs) by … local signals for optimum T
cell activation. The infected tumor … models and elicited an antitumor immunological memory. In …