… Toward this goal, we present a nanotechnology approach to “… multiple overlapping innate
immune pathways could trigger a … promise as vaccine adjuvants that drain to lymph nodes (36). …

… promote lymph node (LN)-targeted delivery in antitumor immune … Hybrid nanoparticle-modified
targeting ligands promoted … LN-targeting and activating the DC-based antitumor immune …

… prophylactic antitumor immunities. Specifically, therapeutic … To further develop lymph
node-targeted delivery of vaccines … synthesized mannose-grafted polymeric nanoparticles to target …

… To further strengthen the anti-tumor immune response … high capacity of draining into lymph
nodes. After being internalized by … Briefly, we obtained target cells from healthy C57BL/6 mice …

… precise antitumor immune responses as novel vaccination … After targeted accumulation at
lymph node (LN) and cellular … in nanotechnology, biological sciences and immune engineering…

… that realize more effective activation of antitumor immunity. … The ICD process can be
triggered by a series of antitumor … Silica nanoparticles have been used to target lymph nodes …

… strategy in improving antitumor immunity by enhancing the … and then trigger CTL and long-term
memory immune responses. … ), but spleen and lymph node still had a strong fluorescence …

… focus on their synthesis for inducing the tumor vaccine. For … MTT could trigger an antitumor
immune response mediated … B cells in the lymph nodes due to the APC-targeting ability of the …

… microenvironment to enhance antitumor immunity. Such … loading nanoparticles migrated
to the lymph nodes, triggering … of PLGA nanoparticles was studied for better DC targeting to …

… vaccines by targeted delivery of antigens to the lymph nodes) … , inducing systematic
antitumor immunity and preventing … uptake of nanoparticles and their transport to lymph nodes, …