… biomolecules enables nanoparticles to actively target peripheral DCs. Once the antigens …
draining lymph node (dLN), where the DCs interact with T cells to trigger anti-tumor immunity. …

… through lymph nodes than larger ones (100 nm), and nanoparticles ranging … enhance the
antitumor immune response.174 Nanomaterials can specifically deliver their cargo to targeted …

… for developing vaccines against hard-to-target infectious … that are capable of activating
innate immunity. As a result, it … antigens migrate to the draining lymph nodes (dLNs) to prime …

… the differentiation of MDSCs toward antitumor immune cells (eg, … CpG ODN to DCs at draining
lymph nodes, compared to free CpG … -targeting gold nanoparticle was used to trigger the …

… vaccines can be targeted to lymph nodes through lymphatic … Lymph node-targeting
nanoparticles are also being used to … A protein nanoparticle vaccine that triggers this FDC …

… leads to subsequent innate and adaptive antitumor immune … Because nanoparticle (NP)-based
vaccine design has been … models resulted in enhanced lymph node accumulation and …

… to lymph nodes, where they engage the adaptive immune system … to target these cell types
to enhance antitumor immune … include engineered liposomal nanoparticle packaging, ex vivo …

… Also, we elaborate on the targets and challenges of … repeat PDT to trigger the robust antitumor
immune response for the … Nanoparticles enhance immunotherapy by targeted remodeling …

… nanoparticles, that are designed to selectively target lymph … -I on DC surfaces, priming and
activating CD8 + T cells, which are … Superior targeting activity and antitumor immune efficacy …

… The nanovaccines efficiently accumulated at the lymph nodes … For proof-of-concept, we
engineered a nanovaccine targeting … the activation of antitumor immune responses (Figure 4j,k). …