… which have unique mechanisms of action targeted specifically to the treatment of OIC. In
this review, we focus on the pharmacologic management of OIC using laxatives, selective 5-HT …

… of 5 community-dwelling Americans with chronic constipation have never … managing their
symptoms and that the use of prescription medicines is very low. Because chronic constipation …

… in mild constipation symptoms but is unlikely to have an effect in patients with severe constipation
[23… the symptoms of constipation and is considered a risk factor for fecal impaction [23]. …

… ) AND (meta-analysis OR systematic review) AND (constipation OR body weight OR obesity
… affects up to 20% of the adult population in North America and negatively affects the quality …

… Of the studies included in this systematic review, only 3 evaluated the effects of treatment on
microbiota composition. Future studies should take into account the actual differences in gut …

… , 52, 57 the majority of the RCTs were conducted in North America, which may affect the
generalisability of the results of this network meta-analysis to patients with IBS-C living in other …

… neuromodulation for chronic constipation remains questionable. In this literature review we
… Sacral neuromodulation, a well-established treatment for urinary and faecal incontinence, is …

… is associated with functional constipation is a matter of debate. A literature review of ten …
in functional constipation in 28–78% of children 25 , and so constipation is sometimes …

… HRQoL in children with functional constipation according to the Rome criteria. … constipation
and if HRQoL was only assessed after successful therapeutic interventions. A meta-analysis …

… This systematic review included 7 studies with a total of 657 older adults in long-term care
settings. All the studies followed a randomised controlled trial design. The studies varied …