… effects of systemically administered MOP agonist morphine in … Equivalent plasma morphine
levels in the 2 rat strains … of morphine dose-dependently increased the number of c-Fos–…

… cells in the deep spinal cord in response to strong suppression action from the midbrain and
pons was … Rats treated with morphine or cocaine did not show pain-like behavior, but c-Fos …

… In the SHAM group, c-Fos immunoreactivity appeared to increase in the entire dorsal horn
laminae I-VI ipsilateral to the formalin injection at the L3-L5 segments. c-Fos immunoreactivity …

… noxious chemical hypersensitivity and stimulus-induced neuronal hyperactivation in the spinal
cord using the formalin pain test combined with c-Fos … Fos expression induced by noxious …

… as a marker of nociception in the present study because c-Fos … analgesics, such as morphine,
suppress phases I and II, … did not consider mechanisms of pain suppression, including the …

… In agreement, the systemic administration of the MLT MT2 … neuropathic morphine-tolerant
rats (crosstolerance), morphine … which was pharmacologically suppressed by the opioid …

… Non-specific immunoreactivity was suppressed by incubating our specimens in a cocktail
of 5% normal donkey serum (Jackson), 1% bovine serum albumin (BSA, Sigma) and 0.3% …

… (D) In contrast to the effect of morphine (C), inhibition of … suppressed reflexive nocifensive
withdrawal from noxious heat; … thalamus show that noxious stimulus-evoked activity in acute …

… At this time the pattern of fos immunoreactivity in the superficial DH following walking in
CFA-treated animals was consistent with noxious stimuli (for a review of fos and nociception in …

… the left side of the heart for distribution to the systemic circulation. … with morphine (as high as
10 mg/kg SC) still showed Fos … 50, 488 suppressess Fos protein-like immunoreactivity in the …