[HTML][HTML] Landscape inferred from gene expression data governs pluripotency in embryonic stem cells
X Kang, C Li - Computational and Structural Biotechnology Journal, 2020 - Elsevier
… study of cell fate decisions on embryonic stem cells has far-… established a model of mouse
embryonic stem cells. We used … model, we performed single factor sensitivity analysis on the …
embryonic stem cells. We used … model, we performed single factor sensitivity analysis on the …
… and perturbation-based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors
R Dries, A Stryjewska, K Coddens, S Okawa… - Stem Cells, 2020 - academic.oup.com
… expression heterogeneity in mouse embryonic stem cells … within a given pathway is during
cell fate/state transitions. … for our systems-level approach that covers different consecutive cell …
cell fate/state transitions. … for our systems-level approach that covers different consecutive cell …
Interlinked bi‐stable switches govern the cell fate commitment of embryonic stem cells
A Giri, S Kar - FEBS letters, 2024 - Wiley Online Library
… Mouse embryonic stem (ES) cells are mainly derived from … After that, we performed the
analysis on the two bistable … network at the molecular and systems level, we have combined three …
analysis on the two bistable … network at the molecular and systems level, we have combined three …
[HTML][HTML] A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells*[S]
… differentiation of human embryonic stems cells (hESCs) in culture. However, the changes that
occur … RNA-Seq analysis reveals different dynamics of differentiation of human dermis- and …
occur … RNA-Seq analysis reveals different dynamics of differentiation of human dermis- and …
Sculpting with stem cells: how models of embryo development take shape
… induced changes in geometry can feedback into cell fate … These free-floating embryonic
stem cell (ESC) aggregates … of the post-implantation mouse embryo, both temporally and …
stem cell (ESC) aggregates … of the post-implantation mouse embryo, both temporally and …
Cell Fate Specification in the Mouse Blastocyst and the Emergence of Pluripotency
V Garg - 2021 - search.proquest.com
… a cellular reprogramming approach between embryonic stem (ES) and eXtraembryonic
ENdoderm (XEN) stem cells – … and regulation to a systems-level view of transcriptional networks …
ENdoderm (XEN) stem cells – … and regulation to a systems-level view of transcriptional networks …
[HTML][HTML] Modeling mammalian commitment to the neural lineage using embryos and embryonic stem cells
… modification analyses, and transcriptome analyses using … In keeping with these changes
in cell fate, the trophectoderm … networks in mouse embryonic stem cells. Maintenance of …
in cell fate, the trophectoderm … networks in mouse embryonic stem cells. Maintenance of …
A System-Level Model Reveals that Transcriptional Stochasticity is Required for Hematopoietic Stem Cell Differentiation
ER Álvarez-Buylla, J Herrera, A Bensussen… - 2024 - researchsquare.com
… hematopoietic stem cells is a process in which cell fates can … number rises, making the
dynamical analysis of large networks … mouse bone marrow hematopoietic stem cell and progenitor …
dynamical analysis of large networks … mouse bone marrow hematopoietic stem cell and progenitor …
Macroscale network feedback structure of transcriptome during cell fate transition
… single-cell transcriptome profiling of developing mouse embryos, we … stem cells diversify into
intermediate progenitors that will … Our analysis characterises key aspects of information flow …
intermediate progenitors that will … Our analysis characterises key aspects of information flow …
A bistable autoregulatory module in the developing embryo commits cells to binary fates
… modeling to dissect the binary cell fate dynamics of the fruit fly … in this section, we restricted
our analysis to a subset of the best … expect small changes in timing to affect the fates of only a …
our analysis to a subset of the best … expect small changes in timing to affect the fates of only a …