[HTML][HTML] Recent advances in the development of toll-like receptor agonist-based vaccine adjuvants for infectious diseases

JX Yang, JC Tseng, GY Yu, Y Luo, CYF Huang… - Pharmaceutics, 2022 - mdpi.com
… girls and young women to prevent cervical disease associated … IgG antibodies and specific
cytotoxic T lymphocyte (CTL) … , well tolerated, and induced high antibody levels to M2e [198]. …

[PDF][PDF] Explore new cancer immunotherapy targets in T cell signaling pathway using proteomic and genetic approaches

W Shang, Y Jiang, A Weiss, W Wang - 2019 - kms.shanghaitech.edu.cn
… Antigens (Ag) from apoptotic HIV-1-infected cells are cross-… to express high levels of TAP2
protein in cervical lesion and … To address this, we established a human T lymphocyte reporter …

SARS-CoV-2 and human immunodeficiency virus: pathogen pincer attack

N Evans, E Martinez, N Petrosillo… - HIV/AIDS-Research …, 2021 - Taylor & Francis
… and proteases for viral entry in uterus, myometrium, ovary, … The mice also had elevated
levels of superoxide radicals, … disease progression in HIV-1infected individuals. Research …

Emerging Challenges in HIV and Aging: Role of a Glycan-Binding Immunomodulatory Lectin

TA Premeaux - 2020 - search.proquest.com
… Our data illustrate a link between cerebrospinal levels of Gal-… the inability of the virus-specific
immune response to delay … by modulating macrophage-T lymphocyte interactions [221]. Gal-…

Identification and selection of immunodominant B and T cell epitopes for dengue multi-epitope-based vaccine

HX Lim, J Lim, CL Poh - Medical microbiology and immunology, 2021 - Springer
… correlated with varying levels of … antibody profiles using the sera of mice vaccinated with
NS1 protein in the presence of different adjuvants. Five immunodominant regions of antibody

[HTML][HTML] NK cell subsets and dysfunction during viral infection: a new avenue for therapeutics?

JC Bjorgen, JK Dick, R Cromarty, GT Hart… - Frontiers in …, 2023 - frontiersin.org
… B varies more in terms of gene content and copy number, although … with weakened cytotoxic
T lymphocyte activity against … shown to mediate migration of virus-specific CD8+ T and NK …

Pharmacological modulation of nucleic acid sensors—therapeutic potential and persisting obstacles

C Vanpouille-Box, JA Hoffmann… - Nature reviews Drug …, 2019 - nature.com
… in monocytes isolated from HIV-1-infected individuals 60 . … an ICB targeting cytotoxic T
lymphocyte-associated protein 4 … is safe and induces robust virus-specific humoral and cellular …

Understanding The Myeloid HIV Reservoir In HIV-Associated Neurological Disorder During Antiretroviral-Treated HIV Infection

BI Mitchell - 2023 - scholarspace.manoa.hawaii.edu
… the peak in the virus-specific CTL response, the virus sequences are observed to change …
the lack of a cellular marker to distinguish HIV-1 infected from uninfected cells; these pose …

[图书][B] The human lung immunoinflammatory network: Development, acute and chronic disease, and aging

R Tirouvanziam, WWJ Unger, SJ Tebbutt - 2023 - books.google.com
… burden, T cell activation and cytokine concentrations in paired BAL and blood from HIV-…
overall milieu in each compartment (Figure 1C). Again, we observed divergent cytokine profiles

Therapeutic vaccines

F Cappuccini, J Kopycinski… - Drug Discovery and …, 2021 - books.google.com
… and known Nef and Pol cytotoxic T-lymphocyte (CTL) epitopes, … Here, HIV-1 infected
individuals receiving ART are … that could be eliminated by virus-specific T cells. Another potential …