… We found that TSP1 and CD47 are upregulated in the lungs of Berkeley (BERK) sickling (…
in BERK mice and the chimeric animals and humans with SCD contributes to vasculopathy …

… in the field of TSP1-CD47 signalling, focusing on several … TSP1-CD47 signalling is
upregulated in diseased human … the development of pulmonary hypertension in mouse models …

… TSP-1 binding to the CD47 … pulmonary hypertension because pulmonary arterial TSP-1
abundance patterns shift in hypoxic hypertensive tissues (14). TSP-1 expression, upregulated by …

… TSP1-CD47 signaling has been reported to be one of the pathogeneses of pulmonary
hypertension … the hypothesis that the upregulation of TSP1-CD47 signaling contributes to PH in a …

… the upregulation of TSP-1 in lung fibroblasts during pulmonary … key signaling pathways
associated with TSP-1 expression … contribution of TSP-1 to fibroblast activation and pulmonary …

… to the loss of TSP1-CD47 signaling, vascular endothelial growth … Correspondingly, loss of
CD47 leads to homeostatic … show that CD47 expression is significantly up-regulated after MI …

… TSP1 and CD47 are upregulated in the lungs of BERK … contributes to endothelial dysfunction.
448 However, it remains to be seen if there is a direct function for TSP1-CD47 signaling to …

… to contribute towards simultaneous vascular dysfunction and subsequent vasculopathy [7,8].
Furthermore, upregulated TSP1 … , plasma TSP1 in patients with pulmonary hypertension can …

… with increased pulmonary artery pressure, pulmonary vascular resistance, and decreased
survival [153]. Mechanistically, binding of TSP-1 to CD47 … -derived TSP-1 contributes to …

… TSP-1 is increased in hypoxic pulmonary hypertension rats, which may contribute to the
pathogenesis of hypoxic pulmonary … The overexpression of TSP1-CD47 signaling in diabetes is …