Persistently high serum substance P levels and early mortality in patients with severe traumatic brain injury

L Lorente, MM Martín, A Pérez-Cejas… - World neurosurgery, 2019 - Elsevier
… Substance P is a neuropeptide belonging to the tachykinin family and is involved in
neuroinflammation. In a previous study by our team, we … Tachykinins and the cardiovascular

[HTML][HTML] The role of pulmonary vascular endothelium in chronic obstructive pulmonary disease (COPD): Does endothelium play a role in the onset and progression of …

S Siragusa, G Natali, AM Nogara… - Exploration of …, 2023 - explorationpub.com
… COPD impairs the cardiovascular system favoring mostly … the tachykinins like substance
P (SP), neurokinin A (NKA), and the calcitonin gene-related peptide (CGRP) [66]. Tachykinins

Medullary tachykinin precursor 1 neurons promote rhythmic breathing

JP Rousseau, A Furdui, C da Silveira Scarpellini… - Elife, 2023 - elifesciences.org
… is comprised of various neuronal populations expressing neurokinin- 1 receptors, the cognate
G- protein- coupled receptor of the neuropeptide substance P (encoded by the tachykinin

Substance P and fibrotic diseases

L Peng, GO Agogo, J Guo, M Yan - Neuropeptides, 2019 - Elsevier
tachykinin 1 (TAC1) gene and belongs to the tachykinin family. SP is widely distributed in the
central nervous system and the peripheral nervous system. … the cardiovascular system are …

[HTML][HTML] Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions

H Yu, W Miao, E Ji, S Huang, S Jin, X Zhu, MZ Liu… - Neuron, 2022 - cell.com
… We further show that tachykinin 1 (Tac1 + ) neurons in the lateral and ventrolateral
periaqueductal gray (l/vlPAG) send monosynaptic excitatory projections to PVH oxytocin neurons. …

[HTML][HTML] Evaluation of substance P as a biomarker for pain in equine colic

N Gruber, S Gesell-May, D Scholler, Y Zablotski… - Journal of Equine …, 2024 - Elsevier
… and massive changes regarding the cardiovascular system. SP is also involved in the central
regulation of the cardiovascular system as tachykinins represent vasoactive peptides which …

Role of the Mast Cell–Neuron Tandem in Cardiac Function Regulation in Cardiovascular Pathologies

MP Morozova, AD Kurenkova, BA Umarova - Journal of Evolutionary …, 2024 - Springer
… Studies of cardiovascular system’s parameters in wild-type (C57BL/6) mice and MC-… -related
peptide (CGRP), SP, and other tachykinins. Various factors can activate these fibers, which …

[HTML][HTML] The role of transient receptor potential vanilloid 1 in common diseases of the digestive tract and the cardiovascular and respiratory system

Q Du, Q Liao, C Chen, X Yang, R Xie, J Xu - Frontiers in Physiology, 2019 - frontiersin.org
system, cardiovascular system and respiratory system in … The cardiac sympathetic afferent
terminals expressing TRPV1 also express many other sensory receptors, such as tachykinins

[HTML][HTML] Two C-terminal isoforms of Aplysia tachykinin–related peptide receptors exhibit phosphorylation-dependent and phosphorylation-independent desensitization …

R Mao, S Guo, G Zhang, Y Li, J Xu, H Wang, P Fu… - Journal of Biological …, 2024 - jbc.org
… the deuterostome tachykinin signaling system, although the role of phosphorylation in
desensitization remains a subject of debate. Here, we describe the signaling system for tachykinin-…

Targeting tachykinin peptides involved in viral infections through in silico approach: Screening the unforeseen potency of serratiopeptidase

A Dhiman, R Purohit - Journal of Molecular Liquids, 2023 - Elsevier
… enzyme by targeting the tachykinin family peptides to deeply understand their relation with
tachykinins. During the onset of any viral infection, overproduction of tachykinins, specifically …