[HTML][HTML] Human gut-associated natural killer cells in health and disease

A Poggi, R Benelli, R Venè, D Costa, N Ferrari… - Frontiers in …, 2019 - frontiersin.org
… on NK cells isolated from peripheral blood mononuclear cells (… vitro against conventional
NK cell targets, but rather produce … + cytotoxic lymphocytes infiltration, and intraepithelial Th17 …

[HTML][HTML] Cytotoxic immunity in peripheral nerve injury and pain

AJ Davies, S Rinaldi, M Costigan, SB Oh - Frontiers in neuroscience, 2020 - frontiersin.org
… We describe how targeted delivery of cytotoxic factors via the … Cytotoxic natural killer cells
form an immunological synapse … minor proportion of peripheral blood cells, NK cells appear to …

OMIP‐069: forty‐color full spectrum flow cytometry panel for deep immunophenotyping of major cell subsets in human peripheral blood

LM Park, J Lannigan, MC Jaimes - Cytometry Part A, 2020 - Wiley Online Library
… NKG2A (CD159a), identified as a possible target for immunotherapy (30), and the activation
… of lymphocytes, monocytes, and dendritic cells present in human peripheral blood. It covers …

[PDF][PDF] Human CD96 correlates to natural killer cell exhaustion and predicts the prognosis of human hepatocellular carcinoma

H Sun, Q Huang, M Huang, H Wen, R Lin… - …, 2019 - Wiley Online Library
… on the cytotoxicity of peripheral blood mononuclear cells (PBMCs… on different target
cells and found that hepatoma cell line HepG2 … Blocking antibodies targeting cytotoxic T-lymphocyte–…

Novel CD19-targeted TriKE restores NK cell function and proliferative capacity in CLL

M Felices, B Kodal, P Hinderlie, MF Kaminski… - Blood …, 2019 - ashpublications.org
… the inflammatory function of NK cells obtained from CLL patient peripheral blood samples.
Finally, we … are innate immune effectors comprising 5% to 15% of blood lymphocytes that are …

[HTML][HTML] T cell activation, highly armed cytotoxic cells and a shift in monocytes CD300 receptors expression is characteristic of patients with severe COVID-19

O Zenarruzabeitia, G Astarloa-Pando, I Terren… - Frontiers in …, 2021 - frontiersin.org
… We have characterized lymphocytes and monocytes from … of T lymphocytes and an increase
in the cytotoxic potential of T … target cells, including virus-infected cells, and activated T …

[HTML][HTML] Overcoming resistance to natural killer cell based immunotherapies for solid tumors

G Nayyar, Y Chu, MS Cairo - Frontiers in oncology, 2019 - frontiersin.org
… the targeted increase in the density of NK cells and lymphocytes in … To increase the targeting
specificity of expanded NK cells, … activities of peripheral blood natural killer cells modified by …

Natural killer cells and anti-tumor immunity

SE Nicholson, N Keating, GT Belz - Molecular immunology, 2019 - Elsevier
… Immunotherapies that target inhibitory receptors on immune cells, such as programmed
cell-death protein 1 (PD1) and cytotoxic T-lymphocyte protein 4 (CTLA-4), have dramatically …

Immunological imprint of COVID‐19 on human peripheral blood leukocyte populations

B Kratzer, D Trapin, P Ettel, U Körmöczi, A Rottal… - Allergy, 2021 - Wiley Online Library
… to and enters the target cells via the angiotensin converting … , T and B lymphocyte populations
we performed whole-blood … -specific B cells or may also exert cytotoxic cellular programs …

[HTML][HTML] Genome engineering of induced pluripotent stem cells to manufacture natural killer cell therapies

K Shankar, CM Capitini, K Saha - Stem cell research & therapy, 2020 - Springer
… of perforin and granzyme B to kill target cells [35]. … from peripheral blood lymphocytes often
results in a heterogenous population of lymphocytes with only a 10–20% yield of NK cells [55]…