… Fibroblast growth factor receptors (FGFRs) have been found to play a vital role in tumorigenesis
and cancer progression through increased cell proliferation… three FGFR family members, …

… cancer, the growing list of investigational FGFR-targeted therapeutics and the available
data from clinical trials and the mechanisms of resistance to FGFR targeted … of FGFR-targeted …

… Here we focus on breast cancer fibroblast growth factors genes aberrations. … The most
common fibroblast growth factor receptors implicated in gene fusions are FGFR2 and FGFR3. The …

… Increasing evidence indicates that aberrant Fibroblast growth factor receptors (FGFR)…
inhibitors targeting FGFRs offer a novel and effective strategy for the therapy of cancers caused by …

… 20 families with nearly 60 members. The Fibroblast Growth Factor Receptor (FGFR) family …
four highly conserved transmembrane receptors (FGFR1–4) and one FGF receptor without an …

… Fibroblast growth factor receptors (FGFRs) are aberrantly activated … fibroblast growth factor
receptor (FGFR) family of receptor tyrosine kinases consists of four transmembrane receptors…

… the growth factors, … fibroblast growth factor receptors (FGFRs). FGF11/12/13/14 do not
interact with the transmembrane FGFRs; of the 22 FGFs, a total of 18 of these function as receptor …

… This study showed that a targeted expression of PSA-NCAM in C6 glioma cells resulted in
increased levels of Olig2, a transcription factor associated with GSCs [75]. While it remains …

… functional cell surface proteins like platelet-derived growth factor receptor β (PDGFRβ) or the
insulin-like growth factor receptor II (IGFRII). Notably, if … bFGF basic fibroblast growth factor …

… By contrast, many other CAF-derived factors, such as fibroblast growth factor 1 (FGF1), uPA
and MMP2, can promote profound breast cancer cell proliferation in a paracrine manner 90 . …