The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… at CpG-rich promoters, gene bodies and transposable elements. We highlight the dynamic
erasure and re-establishment of DNA methylation … , the main targets of DNA methylation in …
erasure and re-establishment of DNA methylation … , the main targets of DNA methylation in …
Spatiotemporal DNA methylome dynamics of the developing mouse fetus
… DNA methylation landscape in the developing mouse … We linked CG-DMRs to their putative
target genes on the basis … First, we overlapped CG-DMRs with promoters, CGIs and CGI …
target genes on the basis … First, we overlapped CG-DMRs with promoters, CGIs and CGI …
DNA methylation reprogramming during mammalian development
Y Zeng, T Chen - Genes, 2019 - mdpi.com
… in promoter regions, are usually devoid of methylation [2]. … the highly dynamic and regulated
processes of DNA demethylation … only loss of methylation, mostly at DNMT3A target loci, in a …
processes of DNA demethylation … only loss of methylation, mostly at DNMT3A target loci, in a …
Dynamics of DNA methylation and its functions in plant growth and development
S Kumar, T Mohapatra - Frontiers in Plant Science, 2021 - frontiersin.org
… , a DNA methyltransferase) for methylation of the target locus. … expression by DNA methylation
in the promoter region and … methylated in the promoter region, which indicates that DNA …
in the promoter region and … methylated in the promoter region, which indicates that DNA …
DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse
… have developed a mouse DNA methylation array that contains 296,070 probes representing
the diversity of mouse DNA methylation … differentiation, while hypomethylation targets AP-1 …
the diversity of mouse DNA methylation … differentiation, while hypomethylation targets AP-1 …
Dynamic enhancer DNA methylation as basis for transcriptional and cellular heterogeneity of ESCs
Y Song, PR van den Berg, S Markoulaki, F Soldner… - Molecular cell, 2019 - cell.com
… defining the relationship between dynamic SE DNA methylation changes, the … target gene
expression, and changes in cellular states. Finally, transgenic methylation reporter mice for …
expression, and changes in cellular states. Finally, transgenic methylation reporter mice for …
Enhancer DNA methylation: implications for gene regulation
A Angeloni, O Bogdanovic - Essays in biochemistry, 2019 - portlandpress.com
… of germline CGI promoters become methylated at early embryonic … more extensive dynamics
at CGIs during development and … , with their putative targets being developmental genes, …
at CGIs during development and … , with their putative targets being developmental genes, …
Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
… Besides expected targets such as Rhox genes 6 , we found … CpG-dense promoter acquire
promoter DNA methylation in WT … We establish that DNA methylation of CpG-island promoters …
promoter DNA methylation in WT … We establish that DNA methylation of CpG-island promoters …
DNA methylation in mammalian development and disease
ZD Smith, S Hetzel, A Meissner - Nature Reviews Genetics, 2024 - nature.com
… DNA methylation dynamics over animal ageing have also drawn substantial interest, either
as potential targets … levels around a typical CpG-rich housekeeping gene promoter during pre-…
as potential targets … levels around a typical CpG-rich housekeeping gene promoter during pre-…
[HTML][HTML] The role of DNA methylation in epigenetics of aging
A Unnikrishnan, WM Freeman, J Jackson… - Pharmacology & …, 2019 - Elsevier
… and intronic regions and under-represented in promoters, CG-islands and specific enhance
… Gene expression is highly dynamic in response to feeding, circadian rthythms and other …
… Gene expression is highly dynamic in response to feeding, circadian rthythms and other …