Hyodeoxycholic acid (HDCA) suppresses intestinal epithelial cell proliferation through FXR‐PI3K/AKT pathway, accompanied by alteration of bile acids metabolism …
M Song, Q Yang, F Zhang, L Chen, H Su… - The FASEB …, 2020 - Wiley Online Library
… been reported that DCA inhibits intestinal cell proliferation via an FXR-… on proliferation and
H2O2-induced apoptosis of intestinal … Taurodeoxycholate increases intestinal epithelial cell …
H2O2-induced apoptosis of intestinal … Taurodeoxycholate increases intestinal epithelial cell …
Molecular mechanisms for protection of hepatocytes against bile salt cytotoxicity
S Morita, Y Ikeda, T Tsuji, T Terada - Chemical and Pharmaceutical …, 2019 - jstage.jst.go.jp
… by ABCB4 is markedly stimulated by TC below the critical … colon cancer cell line HCT116,
deoxycholate and chenodeoxycholate, but not cholate or ursodeoxycholate, induce apoptosis…
deoxycholate and chenodeoxycholate, but not cholate or ursodeoxycholate, induce apoptosis…
Research on gut microbiota-derived secondary bile acids in cancer progression
R Yang, L Qian - Integrative Cancer Therapies, 2022 - journals.sagepub.com
… on TGR5 in HSCs in mice, taurodeoxycholate (TDCA) and … Then they can inhibit the
apoptosis of cancer cells, induce … , then stimulates endothelial cell proliferation and tubular cell …
apoptosis of cancer cells, induce … , then stimulates endothelial cell proliferation and tubular cell …
Taurodeoxycholate, a GPCR19 agonist, ameliorates atopic dermatitis in Balb/c mice
A Ghaderpour, JY Jeong, YH Kim, Y Zou… - European Journal of …, 2023 - Wiley Online Library
… (taurodeoxycholate, TDCA) inhibits the activation of P2X7R. Noncistronically, TDCA inhibits
… DEX drastically decreased spleen weight, because DEX induces apoptosis of splenocytes …
… DEX drastically decreased spleen weight, because DEX induces apoptosis of splenocytes …
[HTML][HTML] Gut microbiota derived bile acid metabolites maintain the homeostasis of gut and systemic immunity
X Su, Y Gao, R Yang - Frontiers in Immunology, 2023 - frontiersin.org
… A reduced number of activated DCs in the colon of mice … PXR activation also inhibits CD8 +
cell proliferation in vitro. … activated B cell apoptosis (100) and inhibits Ig production by B cells (…
cell proliferation in vitro. … activated B cell apoptosis (100) and inhibits Ig production by B cells (…
The effect of bile salts on Porphyromonas gingivalis lipopolysaccharide-induced inflammatory response
박지아 - 2019 - s-space.snu.ac.kr
… taurodeoxycholate promoted the proliferation of intestinal cells and inhibited the apoptosis …
inhibitory effect on IL-6 in the immune cells stimulated by a periodontopathogen Pg-LPS. The …
inhibitory effect on IL-6 in the immune cells stimulated by a periodontopathogen Pg-LPS. The …
Taurocholic acid and glycocholic acid inhibit inflammation and activate farnesoid X receptor expression in LPS-stimulated zebrafish and macrophages
X Ge, S Huang, C Ren, L Zhao - Molecules, 2023 - mdpi.com
… validation, including Taurodeoxycholate acid (TDCA), … the inflammatory damage in the colon
tissue of mice ulcerative … in the liver and secreted to the gastrointestinal tract to facilitate the …
tissue of mice ulcerative … in the liver and secreted to the gastrointestinal tract to facilitate the …
Effect of gut flora mediated‐bile acid metabolism on intestinal immune microenvironment
Y Zhang, X Gao, S Gao, Y Liu, W Wang, Y Feng… - …, 2023 - Wiley Online Library
… LCA inhibits haematopoietic stem cell activation by smad pathway (… Intravenous infusion
of Taurodeoxycholate (TDCA) … induces apoptosis and clearance of genetically altered cells […
of Taurodeoxycholate (TDCA) … induces apoptosis and clearance of genetically altered cells […
The role of bile acids in carcinogenesis
… released into the intestines. In the large intestine, a fraction of primary bile acids is converted
to secondary bile acids by gut bacteria. The majority of the intestinal bile acids undergo …
to secondary bile acids by gut bacteria. The majority of the intestinal bile acids undergo …
Structural modifications that increase gut restriction of bile acid derivatives
… They can also have significant anti-apoptotic effects. As a result, … primarily in the gastrointestinal
tract, especially the colon, it is … Khoruts, Ursodeoxycholic acid inhibits Clostridium difficile …
tract, especially the colon, it is … Khoruts, Ursodeoxycholic acid inhibits Clostridium difficile …