[PDF][PDF] Imaging Biomarkers in Translational Small Animal Models

P Aguiar, F Galli - downloads.hindawi.com
PET and MRI biomarkers in different animal models offers … CBF under various pathological
states can be analysed, and … be integrated into or used to confirm mathematical models to …

[HTML][HTML] Uses of human MR and PET imaging in research of neurodegenerative brain diseases

CG Schwarz - Neurotherapeutics, 2021 - Elsevier
… a map of cerebral blood flow (CBF) or perfusion [73, 74]. … risk (via arterial sampling), and
the practical costs of using the PET … [119], and autoradiography studies have repeatedly found …

[HTML][HTML] PP01-M01

Y Nagai, N Miyakawa, H Takuwa, Y Hori, K Oyama… - Metabolism, 2019 - ncbi.nlm.nih.gov
Autoradiography demonstrated that the binding potential in … the utility of in vivo TSPO PET
imaging in a rat model of low level … at a voxel level, by integrating prior knowledge on spatial …

Drug penetration into the central nervous system: pharmacokinetic concepts and in vitro model systems

F Neumaier, BD Zlatopolskiy, B Neumaier - Pharmaceutics, 2021 - mdpi.com
… brain tissue or the rate of drug delivery by cerebral blood flow (CBF)… plasma, PET
measurements and kinetic modeling allow for … assays or in vitro autoradiography studies, are …

[HTML][HTML] From a demand-based to a supply-limited framework of brain metabolism

S Herculano-Houzel, DL Rothman - Frontiers in Integrative …, 2022 - frontiersin.org
… with our conclusion of a constant OEF o and D o /CBF o ratio. … sensory stimulation using
autoradiography techniques from which … using calibrated fMRI and PET of human cerebral cortex …

… IN ALZHEIMER'S DISEASE: TARGETING BUTYRYLCHOLINESTERASE (BCHE) FOR POSITRON EMISSION TOMOGRAPHY (PET) AND SINGLE PHOTON …

DR DeBay - 2019 - dalspace.library.dal.ca
… from tissue to arterial plasma (simplified tissue compartment … autoradiography revealed that
an Aβ imaging agent, [123I]-2-(… probe, but also its temporal association within target regions …

Cerebral perfusion mapping during retrieval of spatial memory in rats

DP Holschneider, TK Givrad, J Yang, SB Stewart… - Behavioural brain …, 2019 - Elsevier
… blood flow tissue radioactivity with the use of autoradiography. … between tissue radioactivity
and CBF when the data is … temporal resolution and provide signals that are integrated

Molecular Imaging in Neurology

S Vallabhajosula - Molecular Imaging and Targeted Therapy …, 2023 - Springer
… in neuronal tissue for enough time to permit imaging by PET or … CBF has been traditionally
measured quantitatively either as … on the basis of the autoradiographic technique, using …

Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation

…, M Desjardins, MA Yaseen, H Wang… - Journal of Cerebral …, 2022 - journals.sagepub.com
… The OISI module integrated in the multimodal microscope 28 … ΔsO 2 on the venous side
compared to the arterial side, (2) a … measurements of laminar CBF and O 2 metabolism changes …

[PDF][PDF] Non-Invasive measurement of the cerebral metabolic rate of oxygen using MRI in rodents [version 1; peer review

TC Wood, D Cash, E MacNicol, C Simmons, E Kim… - 2021 - pdfs.semanticscholar.org
… to be a cheap, easily available method compared to gold-standard PET measurements. …
of CBF under isoflurane are similar to those reported previously using autoradiography50. …