Neuroimmune interactions in painful TMD: mechanisms and treatment implications

Y Yi, X Zhou, X Xiong, J Wang - Journal of Leukocyte Biology, 2021 - academic.oup.com
… of temporomandibular joint (TMJ), and neurogenic … to neuron excitability amplification, leading
to pain sensitization, … increased in the trigeminal ganglia over the OA chronic pain period. …

… Prevents Suppression of GABAergic Protein Expression in Female Sprague Dawley Trigeminal Ganglion in a Model of Chronic Temporomandibular Joint Disorder

SR Antonopoulos, DA Garten, PL Durham - Archives of Oral Biology, 2024 - Elsevier
excitability, were significantly decreased on day 14 post jaw … within the dorsal root ganglion
alleviated hypersensitivity to … , it is likely that GSE could potentiate the effect of baclofen by …

Estrogen Status and Trigeminal Ganglion Responses to Jaw Movement

X Zhang, M Rahman… - Journal of dental …, 2022 - journals.sagepub.com
… mild tissue inflammation and estrogen status influenced the responses of trigeminal ganglion
neurons to jaw palpation or jaw … Chronic temporomandibular joint disorders (TMDs) are …

Towards a Better Understanding of Temporomandibular Disorder

JR Cox - 2019 - bearworks.missouristate.edu
… of developing temporomandibular joint disorders (TMJD), which … function to regulate the
excitability state of the neurons.The … vasodilator and potentiates protein extravasation, stimulates …

… occlusal interference-induced chronic masseter hyperalgesia by increasing the neuronal excitability and TRPV1 function of trigeminal ganglion in ovariectomized rats

Y Liu, XX Xu, Y Cao, SY Mo, SS Bai, YY Fan… - International Journal of …, 2021 - mdpi.com
… of the masticatory muscles and/or temporomandibular joints (… expression levels in the dorsal
root ganglion (DRG) in mice [… that neuronal excitability was rapidly potentiated. Although this …

Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain

Y Zhang, N Song, F Liu, J Lin, M Liu, C Huang… - International journal of …, 2019 - nature.com
… neuralgia, temporomandibular joint disorders, migraine and … In the dorsal root ganglion
(DRG) of the spinal cord, there is … IL-1β and TNF-α enhanced the excitability of neurons by …

[HTML][HTML] Increased substance P and synaptic remodeling occur in the trigeminal sensory system with sustained osteoarthritic temporomandibular joint sensitivity

MM Sperry, EJ Granquist, BA Winkelstein - Pain Reports, 2021 - journals.lww.com
… loading alters expression of proteins associated with neuronal excitability in the Sp5C and …
is linked to long-term synaptic potentiation in secondary neurons, 13 synaptic remodeling was …

Dietary constituent genistein inhibits the hyperexcitability of trigeminal nociceptive neurons associated with mechanical hyperalgesia following orofacial inflammation

S Arakawa, M Inoue, R Kinouchi, S Morizumi… - Journal of Oral …, 2019 - Elsevier
… suppresses the excitability of trigeminal ganglion neurons in vitro [7]. … -sensitive nociceptive
trigeminal ganglion neurons via … - and medium-sized dorsal root ganglion neurons, such as …

Plastic changes in nociceptive pathways contributing to persistent orofacial pain

M Shinoda, S Hitomi, K Iwata, Y Hayashi - Journal of Oral Biosciences, 2022 - Elsevier
… for pathological orofacial pain such as temporomandibular joint dysfunction, myofascial …
trigeminal nerve injury potentiates TG neuronal excitability, thereby causing orofacial pain

[HTML][HTML] Peripheral and central mechanisms of persistent orofacial pain

M Shinoda, A Kubo, Y Hayashi, K Iwata - Frontiers in Neuroscience, 2019 - frontiersin.org
excitability in the uninjured trigeminal nerve branches is altered by NO signaling, the injured
neurons and increased excitability … -like receptor 2 potentiates the abundance of activated …