The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods
… The core content of the ChEMBL database is published bioactivity data, from a set …
error-checking user data. The documentation also covers common errors and issues in deposited …
error-checking user data. The documentation also covers common errors and issues in deposited …
JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles
JA Castro-Mondragon, R Riudavets-Puig… - … acids research, 2022 - academic.oup.com
… data-type specific; we maintained the CORE and Unvalidated … question is what fraction of
TFs have a binding profile in JASPAR. For humans, the JASPAR vertebrates CORE collection …
TFs have a binding profile in JASPAR. For humans, the JASPAR vertebrates CORE collection …
Comparative toxicogenomics database (CTD): update 2023
AP Davis, TC Wiegers, RJ Johnson… - … acids research, 2023 - academic.oup.com
… events) to filter the data set to 601 tetramers composed of 11 chemicals, 62 genes and 88
phenotypes (Figure 1C). Finally, researchers can manually consolidate the tetramers to …
phenotypes (Figure 1C). Finally, researchers can manually consolidate the tetramers to …
The European nucleotide archive in 2022
J Burgin, A Ahamed, C Cummins, R Devraj… - … acids research, 2023 - academic.oup.com
… established for 40 years as a database of record for nucleotide sequence … data for biodiversity
research, covering different data resources eg molecular biology, natural history collections…
research, covering different data resources eg molecular biology, natural history collections…
miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions
… biomedical corpus to solve the problem that ordinary text mining … Here, we collected
comprehensive miRNA expression … between ‘biochemistry and molecular biology’ and ‘oncology’ …
comprehensive miRNA expression … between ‘biochemistry and molecular biology’ and ‘oncology’ …
The UCSC genome browser database: 2023 update
… 1) is an online resource for the genomics community providing data access and visualization…
) (15), which aims to collect and standardize gene-disease validity annotations across …
) (15), which aims to collect and standardize gene-disease validity annotations across …
The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
… safety issues can also influence the prioritisation strategy. A new ‘Genetic Constraint’ data
widget … model, the newly developed Spark extract-transform-load pipeline produces a set of …
widget … model, the newly developed Spark extract-transform-load pipeline produces a set of …
The ProteomeXchange consortium at 10 years: 2023 update
EW Deutsch, N Bandeira, Y Perez-Riverol… - … acids research, 2023 - academic.oup.com
… between the submitted data and the metadata collected. … be reanalysed using sequence
databases constructed by eg … potential legal issues of this type, they should submit their data to …
databases constructed by eg … potential legal issues of this type, they should submit their data to …
InterPro in 2022
T Paysan-Lafosse, M Blum, S Chuguransky… - … acids research, 2023 - academic.oup.com
… To resolve this issue, we have redesigned the menu, it is … field of molecular biology and
biomedical research. DeepMind … amino acid sequences using Pfam families as a training set (31)…
biomedical research. DeepMind … amino acid sequences using Pfam families as a training set (31)…
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
D Szklarczyk, R Kirsch, M Koutrouli… - … acids research, 2023 - academic.oup.com
… dedicated to data integration in the protein network context have been developed. These
resources aim to collect and critically assess protein–protein functional linkage data, integrate it…
resources aim to collect and critically assess protein–protein functional linkage data, integrate it…