Evolutionary engineering of Corynebacterium glutamicum

RG Stella, J Wiechert, S Noack… - Biotechnology …, 2019 - Wiley Online Library
… power of evolution to improve process performance. Rational … the metabolic and regulatory
function of gene products,54, … mutations having a negative impact on genome stability. Often, …

Biosystem design of Corynebacterium glutamicum for bioproduction

J Zha, Z Zhao, Z Xiao, T Eng, A Mukhopadhyay… - … in Biotechnology, 2023 - Elsevier
… uses allelic exchange plasmids, which is a multistep and overall inefficient process. Better
geneglutamicum genome editing through optimized expression of guide RNA and Cas9 and …

Genome-Reduced Corynebacterium glutamicum Fit for Biotechnological Applications

VF Wendisch - Minimal Cells: Design, Construction, Biotechnological …, 2019 - Springer
… ) impacts genome reduction and how highly parallel genome editing … , makes use of
biotechnology for the sustainable processingCorynebacterium glutamicum is a central pillar of …

Advances and Perspectives for Genome Editing Tools of Corynebacterium glutamicum

Q Wang, J Zhang, NH Al Makishah, X Sun… - Frontiers in …, 2021 - frontiersin.org
Corynebacterium glutamicum has been considered a promising synthetic biological
platform for biomanufacturing and bioremediation. However, there are still some challenges in …

Physiological characteristics of Corynebacterium glutamicum as a cell factory under anaerobic conditions

Y Tsuge, A Yamaguchi - Applied Microbiology and Biotechnology, 2021 - Springer
Corynebacterium glutamicum, a gram-positive and facultative anaerobic bacterium, is
widely used for the industrial production of amino acids, such as l-glutamate and l-lysine. C. …

[HTML][HTML] Production of l-glutamate family amino acids in Corynebacterium glutamicum: physiological mechanism, genetic modulation, and prospects

Q Sheng, XY Wu, X Xu, X Tan, Z Li, B Zhang - … and Systems Biotechnology, 2021 - Elsevier
Corynebacterium glutamicum, a GRAS strain accumulated … in 1956, providing a feasible
process for the fermentative production of amino … glutamicum harboring the sacC gene from M. …

High-Quality Genome-Scale Reconstruction of Corynebacterium glutamicum ATCC 13032

M Feierabend, A Renz, E Zelle, K Nöh… - Frontiers in …, 2021 - frontiersin.org
… belongs to the microbes of enormous biotechnological … A deep understanding of the
biochemical processes in C. … function becomes more apparent when looking at the effects of …

[HTML][HTML] Industrial production of L-lysine in Corynebacterium glutamicum: Progress and prospects

J Liu, JZ Xu, ZM Rao, WG Zhang - Microbiological Research, 2022 - Elsevier
process of Corynebacterium glutamicum producing L-lysine. … -lysine, its expression
directly affects the efficiency of product … of the global factor encoding gene lrp. At present, …

Application of Corynebacterium glutamicum engineering display system in three generations of biorefinery

K Lin, S Han, S Zheng - Microbial Cell Factories, 2022 - Springer
… through gene editing (Fig. 2), and a series of methods have been developed for C. … used
as a production host of aromatic compounds involved in biotechnology [69, 93]. At present, …

The soil bacterium, Corynebacterium glutamicum, from biosynthesis of value-added products to bioremediation: A master of many trades

D Ray, U Anand, NK Jha, E Korzeniewska… - Environmental …, 2022 - Elsevier
… in the field of industrial and environmental biotechnology (… procedures, have been used
to introduce mutations into the … glutamicum R genome consists of a circular 3 314 179 bp …