… short half-life as a result of ubiquitination and proteasomal degradation. This is caused by
an exclusive 18-residue loop that mediates binding to 2 ubiquitin ligases (15–17). This loop …

… cells that express the activating type 2 deiodinase (D2) have … express type 3 deiodinase
(D3), the inactivating deiodinase. … , “local” deiodinase-mediated mechanisms within target cells …

… passage of both T4 and T3 through the blood brain barrier and local cells; (ii) deiodinases …
the triad that mediates TH signaling in the rodent brain (such as transporters, deiodinases, TRs…

… by ubiquitination, which is mediated by the E3 ubiquitin ligases WSB-1 and/or the yeast Doa10
mammalian ortholog TEB4. … DIO2 could be either targeted for proteasomal degradation or …

… the Teb4/Doa10 domain, both with as yet unknown functions. … familial intrahepatic cholestasis
type II (PFIC II) where there is … SM's cholesterol mediated degradation via ubiquitination [85]…

… The selenocysteine binding protein 2 (Secisbp2) mediates the insertion of selenocysteine in
… UBC6 and UBC7 ubiquitin-activating enzymes, and the WSB-1 and TEB-4 ubiquitin ligases …

… is mediated by the type 2 deiodinase (D2). To study D2-… T4-induced D2 ubiquitination and
degradation in the proteasomes, … , 2 ubiquitin ligases previously involved in D2 ubiquitination (…

… yeast homolog, Doa10, is one of two key E3 ligases that mediate ER-associated degradation.
… The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. …

… reticulum–mediated degradation of selenoproteins via ubiquitin-… -RING E3 ubiquitin ligase
2 targets the defective proteins for … ring-CH-type finger 6 (MARCH6, also called TEB4) are …

… , type 2 iodothyronine deiodinase (D2), squalene monooxygenase (SQLE) and perilipin …
The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. Mol …