Dysregulation of the Hippo pathway signaling in aging and cancer

YT Yeung, A Guerrero-Castilla, M Cano… - Pharmacological …, 2019 - Elsevier
… expression via activation of TEAD transcription factors. This … of core components of the
Hippo pathway, upstream signaling … The ETS family member, GA-binding protein (GABP), also …

ETS transcription factors: multifaceted players from cancer progression to Tumor immunity

Y Wang, Z Huang, M Sun, W Huang, L Xia - Biochimica et Biophysica Acta …, 2023 - Elsevier
… (A) The association heatmap of ETS TFs expression in pan-cancer. (B) The association
heatmap between ETS transcription factors expression and immune cells in malignancies of the …

[PDF][PDF] Integration of Hippo-YAP signaling with metabolism

C Ibar, KD Irvine - Developmental cell, 2020 - cell.com
… enable Hippo-YAP signaling to coordinate organ growth and … transcription factors of the
Hippo pathway as YAP proteins). … as well as other components of the Hippo signaling network, …

The hippo pathway: A master regulator of liver metabolism, regeneration, and disease

AT Nguyen‐Lefebvre, N Selzner, JL Wrana… - The FASEB …, 2021 - Wiley Online Library
… review a list of pharmacological components targeting the Hippo pathway members and its
… The Ets transcription factor GABP is a component of the hippo pathway essential for growth

[HTML][HTML] Hepatic Hippo signaling inhibits development of hepatocellular carcinoma

Y Liu, X Wang, Y Yang - Clinical and Molecular Hepatology, 2020 - ncbi.nlm.nih.gov
… A key component of the Hippo pathway is the inhibition of yes… Hippo signaling pathway as
a key regulator of liver growth … other transcription factors and oncogenic signaling pathways

[HTML][HTML] Effects of quinacrine on expression of hippo signaling pathway components (LATS1, LATS2, and YAP) in human breast cancer stem cells

S Darbankhales, R Mirfakhraie… - Asian Pacific Journal …, 2020 - ncbi.nlm.nih.gov
… the Hippo signaling pathway has a significant effect on growth of … , some transcription
factors such as TEAD family transcriptionGABP an Ets transcription factor family, c-Jun, β-catenin/…

Role of the transcriptional coactivators YAP/TAZ in liver cancer

S Zhang, D Zhou - Current opinion in cell biology, 2019 - Elsevier
… demonstrated that the genetic disruption of Hippo signaling components NF2, WW45, and
… To date, several transcription factors including Ets transcription factor family GABP, c-Jun, β-…

The Hippo signaling pathway in regenerative medicine

L Hong, Y Li, Q Liu, Q Chen, L Chen, D Zhou - The Hippo Pathway …, 2019 - Springer
… ), the core components of Hippo signaling, results in YAP activation and sustained liver growth,
… This chapter provides a detailed description of procedures and important considerations …

Oxidative stress-CBP axis modulates MOB1 acetylation and activates the Hippo signaling pathway

J Jin, L Zhang, X Li, W Xu, S Yang, J Song… - Nucleic Acids …, 2022 - academic.oup.com
… , and thereby controls tissue growth, embryonic development … is an important co-activator in
the Hippo pathway, belonging … an important component of the Hippo signaling pathway and …

It takes two to tango: coupling of Hippo pathway and redox signaling in biological process

J Zheng, H Yu, A Zhou, B Wu, J Liu, Y Jia, L Xiang - Cell Cycle, 2020 - Taylor & Francis
… of protein kinases and transcription factors. Meanwhile, oxidative … Upon the loss of Hippo
signaling, GABP translocates to the … redox milieu and Hippo components provides an attractive …