[HTML][HTML] Insights into therapy resistance in cervical cancer

IA George, R Chauhan, RE Dhawale, R Iyer… - Advances in Cancer …, 2022 - Elsevier
… the high-risk viruses such as HPV 16 and 18 are involved in 70… as well as protein, has been
reported in cervical cancer and it … associated with radiation resistance in cervical cancer [127,…

[HTML][HTML] Human papillomavirus type 18 E5 oncoprotein cooperates with E6 and E7 in promoting cell viability and invasion and in modulating the cellular redox state

J Hochmann, F Parietti, J Martínez… - Memórias do Instituto …, 2020 - SciELO Brasil
… premalignant lesion and in cervical cancer are HPV-16 (46-63… HPV16 E6 and E7 proteins
cooperate to immortalize human … B-irradiation-induced apoptosis. J Virol. 2002; 76(1): 220-31. …

Carbon-ion irradiation overcomes HPV-integration/E2 gene-disruption induced radioresistance of cervical keratinocytes

N Arians, NH Nicolay, S Brons… - Journal of Radiation …, 2019 - academic.oup.com
… and local control in cervical carcinomas [4–6]. Additionally, … status of HPV 16 influences the
radiosensitivity of cervical … a specific radiation dose that matches normal or resistant cells [30], …

[HTML][HTML] Biological and clinical aspects of HPV-related cancers

KA Szymonowicz, J Chen - Cancer biology & medicine, 2020 - ncbi.nlm.nih.gov
… body radiation applies high doses of radiation into the tumorcervical cancer cells after
downregulating HPV 16 E6 and … cisplatin resistance in cervical cancer, different proteins have …

Advances in molecular mechanism of HPV16 E5 oncoprotein carcinogenesis

B Chen, L Zhao, R Yang, T Xu - Archives of Biochemistry and Biophysics, 2023 - Elsevier
… great significance to study the molecular mechanism of cervical cancer caused by HPV16. …
HPV16 E5 expression in human keratinocytes is resistant to ultraviolet (UV)-B radiation-…

[图书][B] Investigating Biological Mechanisms of Radiation Resistance in Advanced Stage Cervical Cancer

F Ruiz - 2019 - search.proquest.com
… between HpV 16 and other HpV genotypes in cervical cancere6, affects cellular response
to chemotherapy and radiationHpV 16 e6 and e6ki protein coding sequences were ligated …

[HTML][HTML] Immune signature-based subtypes of cervical squamous cell carcinoma tightly associated with human papillomavirus type 16 expression, molecular features …

X Lu, L Jiang, L Zhang, Y Zhu, W Hu, J Wang, X Ruan… - Neoplasia, 2019 - Elsevier
… way to treat cervical cancer, we tried to assess the response of two HPV16 subtypes to two
… of platinum-based chemotherapy and radiation. Using the GDSC database, we imputed that …

[HTML][HTML] Molecular mechanisms underlying increased radiosensitivity in human papillomavirus-associated oropharyngeal squamous cell carcinoma

H Wang, B Wang, J Wei, L Meng, Q Zhang… - … Journal of Biological …, 2020 - ncbi.nlm.nih.gov
… principles of tumor cell damage caused by radiation, including … considered an important
cause of cervical cancer. It has also … Similarly, in mouse models, the expression of HPV16-E7, …

Increased expression of HPV-E7 oncoprotein correlates with a reduced level of pRb proteins via high viral load in cervical cancer

BA Mir, A Ahmad, N Farooq, MV Priya, AH Siddiqui… - Scientific Reports, 2023 - nature.com
… A total of 105 HPV-16 positive cervical cancer tissue samples and 30 HPV negative non-cancerous
samples from patients who are suffering from some gynecological problems not …

Cervical carcinoma: oncobiology and biomarkers

LV Volkova, AI Pashov, NN Omelchuk - International journal of molecular …, 2021 - mdpi.com
cervical cancer, it was found that after irradiation, patients … of resistance to therapy of
various types of cervical cancer are … in cervical cancer tumor samples associated with HPV16