CENPM upregulation by E5 oncoprotein of human papillomavirus promotes radiosensitivity in head and neck squamous cell carcinoma
T Liu, L Ma, L Song, B Yan, S Zhang, B Wang, N Zuo… - Oral Oncology, 2022 - Elsevier
… and revealed that the Centromere Protein M (CENPM) … of HPV16 E5, E6, E6* (a splicing
isoform of E6), or E7 in HPV-… that cells became more resistance to radiation, while the proportion …
isoform of E6), or E7 in HPV-… that cells became more resistance to radiation, while the proportion …
… review on cross-talk of human papilloma virus oncoproteins and developmental/self-renewal pathways during the pathogenesis of uterine cervical cancer
A Ahmad, IA Ansari - Current Molecular Medicine, 2021 - ingentaconnect.com
… radio- and drug-resistant cervical cancer. Therefore, this review … in the attainment of
radioresistance in cervical cancer [74]. A … Selective targeting of HPV16 E6/E7 in cervical cancer …
radioresistance in cervical cancer [74]. A … Selective targeting of HPV16 E6/E7 in cervical cancer …
Local radiotherapy and E7 RNA-LPX vaccination show enhanced therapeutic efficacy in preclinical models of HPV16+ cancer
N Salomon, A Selmi, C Grunwitz, A Kong… - Cancer Immunology …, 2022 - Springer
… The HPV E6 and E7 proteins are oncogenic drivers and thus … E7 RNA-LPX synergizes with
LRT in HPV16 + mouse tumors, … characterized radiation-mediated effects on the local tumor …
LRT in HPV16 + mouse tumors, … characterized radiation-mediated effects on the local tumor …
Association Between E6 and E7 Human Papilloma Virus Type 16 Oncogen Mutations and P21 Protein Expression in Cervical Cancer
… Increased HOTAIR could induce radio-resistance by inhibiting p21 protein in … of E6 and E7
HPV16/18 was associated with the expression of TMPOP2 in CaSki and HeLa cervical cancer …
HPV16/18 was associated with the expression of TMPOP2 in CaSki and HeLa cervical cancer …
NRF2, p53, and p16: predictive biomarkers to stratify human papillomavirus associated head and neck cancer patients for de-escalation of cancer therapy
PS Ramesh, D Devegowda, A Singh… - Critical reviews in …, 2020 - Elsevier
… Beyond any doubt, HPV infection prominently HPV16 (… ve cervical cancer cell lines and
inhibited the growth of tumor … of HPV +ve cancer cells to the combined treatment of irradiation and …
inhibited the growth of tumor … of HPV +ve cancer cells to the combined treatment of irradiation and …
HPV16 E5 mediates resistance to PD-L1 blockade and can be targeted with rimantadine in head and neck cancer
S Miyauchi, PD Sanders, K Guram, SS Kim, F Paolini… - Cancer research, 2020 - AACR
… of overall cancer worldwide including cervical cancer and head … whether radiation combined
with CBI could enhance local tumor … of HPV viral proteins. Although the functions of HPV …
with CBI could enhance local tumor … of HPV viral proteins. Although the functions of HPV …
TP53 mutants and non-HPV16/18 genotypes are poor prognostic factors for concurrent chemoradiotherapy in locally advanced cervical cancer
I Kuno, D Takayanagi, Y Asami, N Murakami… - Scientific Reports, 2021 - nature.com
… E6 and E7 proteins form complexes with p53 and … radioresistance or poor prognosis in
cervical cancer. In our study, patients without HPV16/18 had poorer PFS than those with HPV16/…
cervical cancer. In our study, patients without HPV16/18 had poorer PFS than those with HPV16/…
RETRACTED ARTICLE: Molecular mechanisms in progression of HPV-associated cervical carcinogenesis
SM Gupta, J Mania-Pramanik - Journal of biomedical science, 2019 - Springer
… Cervical cancer is the fourth most frequent cancer in women … Of these, HPV16 and
HPV18 are the most important types, … All these molecular alterations facilitate resistance to …
HPV18 are the most important types, … All these molecular alterations facilitate resistance to …
[HTML][HTML] Significant growth inhibition by a bispecific affibody targeting oncoprotein E7 in both HPV16 and 18 positive cervical cancer in vitro and in vivo
X Tan, J Yang, J Jiang, W Wang, J Ren, Q Li… - European Journal of …, 2022 - Elsevier
… To clarify the molecular mechanisms through which affibodies target the protein E7 to inhibit
the growth of cervical cancer cells, we first confirmed the binding specificity of affibodies to …
the growth of cervical cancer cells, we first confirmed the binding specificity of affibodies to …
The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation
JA Scarth, MR Patterson… - Journal of General …, 2021 - microbiologyresearch.org
… Indeed, the majority of HPV16-associated cervical cancer … to ultraviolet (UV)-B radiation;
this requires E5-dependent … the E7 protein in high-grade cervical neoplasia and cervical …
this requires E5-dependent … the E7 protein in high-grade cervical neoplasia and cervical …