… 1 and UV radiation resistance-associated gene protein. To … the E6/E7 depletion promoted
autophagy in the cervical cancer … who reported that HPV16 and 18 positive cervical cancer …

… the protein expression profiles of HR-HPV E7 types (HPV16 … HPV16 E7 was also reported
to have conferred resistance to … and can contribute to radioresistance and chemoresistance, …

… -1 protein (Nurr1) was upregulated in primary cervical cancer … In addition, the chemo-
and radio-resistant nature of CSLCs … transiently silenced HPV E6 with siRNA in HPV16-positive …

… that offer similar oncologic outcomes to radiation, with less treatment … HPV16 E6 ∗ II gene
expression in intraepithelial cervical … can have profound effects at the protein level (Figure 1F). …

… HPV+ HNC are more sensitive to radiation than HPV− HNC and … in CENP-E protein, we
analyzed tumor protein lysates of a second … We then extended this analysis to cervical cancer. …

… (HPV) oncoprotein E6 and E6-associated protein (E6AP) ubiquitin … of cervical carcinoma
include surgery, radiation as well as … HPV 16 is found in approximately 50% of the CC cases, …

… in cervical cancer,2 HPV16 and HPV18 being responsible for >70% of all cervical cancer …
be 5-fold to 10-fold more resistant to hydrolysis and induced significant serum levels of IFN-γ…

… - and chemotherapy resistance, and inhibit tumor growth in … to protein degradation; (8)
HPV-encoded E6 can form a protein … is that HPV E6 can inhibit p53, thereby ablating irradiation-…

… were isolated upon selection of cells resistant to G418: U-… To confirm this in our cellular
models, the radiation sensitivity … mediated by HPV16 E6*I RNA rather than the E6*I protein 38 . …

… A tumor suppressor protein p16INK4a produced as a result … of tumor hypoxia and this shift
reflects the radioresistance that … EMT upregulation is thought to be mediated by HPV 16 E6 as …