Antigen-specific therapeutic approaches for autoimmunity

P Serra, P Santamaria - Nature biotechnology, 2019 - nature.com
regulation (defined as the ability to suppress both cognate and noncognate lymphocyte
specificities involved in a given immune response) do … may represent heterogeneous mixtures of …

Cytokine-mediated communication: a quantitative appraisal of immune complexity

G Altan-Bonnet, R Mukherjee - Nature Reviews Immunology, 2019 - nature.com
… cell types can regulate the balance between immune tolerance and immune response, thus
… analysed to show how the heterogeneous activation of T H cells can be modulated by T reg …

[HTML][HTML] Innate-adaptive immunity interplay and redox regulation in immune response

L Sun, X Wang, J Saredy, Z Yuan, X Yang, H Wang - Redox biology, 2020 - Elsevier
… adaptive immune cells which convey antigen-specific immune … The natural antibodies
produced by B1 cells differ from B2 … channel and involved in osmotic volume regulation. Recently, …

Regulation of immune responses by the airway epithelial cell landscape

RJ Hewitt, CM Lloyd - Nature Reviews Immunology, 2021 - nature.com
… is illuminating the cellular heterogeneity that exists in the … R, which regulates the number and
function of murine airway … cells can shape the immune response to environmental antigens. …

Immunomodulation by endothelial cells—partnering up with the immune system?

J Amersfoort, G Eelen, P Carmeliet - Nature Reviews Immunology, 2022 - nature.com
… vessels are known to regulate various aspects of immunity 1,2 … Lymph nodes contain a
vascular bed with a heterogeneous … an adequate immune response against harmful antigens. …

Chemokines and the immune response to cancer

AJ Ozga, MT Chow, AD Luster - Immunity, 2021 - cell.com
… the tumor microenvironment regulate the overall chemokine … TME in the context of the
heterogeneity of solid tumors at the … -tumor T cell responses depends on antigen-presenting cells (…

Neuronal regulation of immunity: why, how and where?

M Schiller, TL Ben-Shaanan, A Rolls - Nature Reviews Immunology, 2021 - nature.com
… be relevant for brain–immune system communication, our goal … For example, the number
of circulating leukocytes oscillates … tract constantly encounters new antigens. Thus, there is an …

Antigen presentation by dendritic cells and their instruction of CD4+ T helper cell responses

KL Hilligan, F Ronchese - Cellular & molecular immunology, 2020 - nature.com
… cell biology, their heterogeneity, and the properties of different … A number of factors are
implicated in regulating the Th cell … for IL-12 in Th1 immune responses, signals that regulate IL-12 …

Autophagy in the renewal, differentiation and homeostasis of immune cells

AJ Clarke, AK Simon - Nature Reviews Immunology, 2019 - nature.com
… Across all branches of the immune system, the process of … There is also considerable
heterogeneity between different tissues in … be emphasized that our understanding of the regulatory

Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
… they include regulatory feedback. While the wrapping of … For example, antibodies can also
bind to the polyanionic … than peripheral regions and this heterogeneity was more apparent for …