The bifunctional transporter‐receptor IRT 1 at the heart of metal sensing and signalling

V Cointry, G Vert - New Phytologist, 2019 - Wiley Online Library
Arabidopsis genome encodes about 1200 transporters involved in the uptake, the short- and
long-distance … or the excretion of a wide variety of substrates in the plant. Their functional …

Root‐to‐shoot iron partitioning in Arabidopsis requires IRON‐REGULATED TRANSPORTER1 (IRT1) protein but not its iron (II) transport function

J Quintana, M Bernal, M Scholle… - The Plant …, 2022 - Wiley Online Library
… of the life cycle of Arabidopsis thaliana without vigorous Fe … in the range of those in shoots
of the WT (Figure 1(d)). The … There was large quantitative variation and total Fe uptake …

Differential metal sensing and metal‐dependent degradation of the broad spectrum root metal transporter IRT1

J Spielmann, V Cointry, F Devime, S Ravanel… - The Plant …, 2022 - Wiley Online Library
… Fe serves as a major cofactor for a wide range of electron … In the model plant Arabidopsis
thaliana, and more generally … the micromolar range (19.5 ± 6.3 μm) for Zn for the IRT1 wild-…

Endocytosis in plants: peculiarities and roles in the regulated trafficking of plant metal transporters

R Ivanov, G Vert - Biology of the Cell, 2021 - Wiley Online Library
… plant Arabidopsis thaliana, and our current understanding of their roles for the regulation of
… Fe deficiency, however due to the broad IRT1 substrate range, other metals, such as Mn, Zn …

Birth, life and death of the Arabidopsis IRT1 iron transporter: the role of close friends and foes

A Abuzeineh, G Vert, E Zelazny - Planta, 2022 - Springer
… including the model plant Arabidopsis thaliana, iron uptake by … that are located in the large
cytosolic loop of IRT1. Indeed, … and long-range interactions of membrane proteins. The recent …

Calcium-promoted interaction between the C2-domain protein EHB1 and metal transporter IRT1 inhibits Arabidopsis iron acquisition

I Khan, R Gratz, P Denezhkin… - Plant …, 2019 - academic.oup.com
… the model plant Arabidopsis (Arabidopsis thaliana) requires … cells resulted in a broad
localization pattern with signals visible … E, Distance between the calcium ions bound to the protein

Ferrous iron uptake via IRT1/ZIP evolved at least twice in green plants

WFC Rodrigues, ABP Lisboa, JE Lima… - New …, 2023 - Wiley Online Library
Arabidopsis thaliana, for … transporter-like proteins can transport a broad range of metal
other than Fe, such as zinc (Zn) and manganese (Mn). In fact, in addition to Arabidopsis IRT1, the …

[HTML][HTML] Multilayered regulation of iron homeostasis in Arabidopsis

J Spielmann, S Fanara, V Cotelle, G Vert - Frontiers in Plant Science, 2023 - frontiersin.org
… In the model plant Arabidopsis thaliana, strategy I is driven by a complex of three proteins
First, the high influx rate of non-Fe metals is directly sensed by IRT1 through non-Fe metal

Metal transporters in organelles and their roles in heavy metal transportation and sequestration mechanisms in plants

A Jogawat, B Yadav, Chhaya… - Physiologia …, 2021 - Wiley Online Library
… to the upregulation of iron transporters IRT1 and FRO2 in roots… range of metals, usually
inside vacuoles for disposing of them. There are eight identified members in Arabidopsis thaliana

The root iron transporter 1 governs cadmium uptake in Vicia sativa roots

X Zhang, X Li, L Tang, Y Peng, M Qian, Y Guo… - Journal of Hazardous …, 2020 - Elsevier
… Cd content of yeasts cultured in liquid medium containing a broad range of Fe, Zn or Mn …
IRT1, a key regulator of Fe acquisition, is a metal transporter with a broad spectrum of substrates