… of Treg decreases viral load and restores the activity of virus-specific cytotoxic CD8 + T cells
(91, 92). On the other hand, it has been found that the role of Treg depends on the disease …

… The suppressive function of a class of T cells was first reported by Gershon and Kondo … T
cells during inflammation was distinct from helper T cells (T H cells), hypothesizing that T cells …

… of functional cytotoxic CD8 + T cells, the inhibition of myeloid-derived suppressive cells and
regulatory T cells, and … which acquired enhanced specific and effective antitumor activity.98 …

… MicroRNAs (miRNAs) are a naturally occurring class of small … cellular processes, development,
cell differentiation, and … of regulatory T cells via suppression of several effector T cell …

… differentiate into distinct effector subsets through the activity of different TFs, such as T-bet
for T … [61], RORγt for Th17 cells [62], and forkhead box P3 (Foxp3) for regulatory T cells (Treg …

… of cells with high-affinity antibodies through regulation of … of IL-17-producing T helper cells
(T H 17 cells) in response to T cell … evidence that the activity of several miRNAs is subcellularly …

… better clinical outcomes following therapy [23,24]. However, higher ratios of FoxP3 + Tregs:CD8
+ T cell … -3 and TIGIT can increase the suppressive activity of Tregs as measured by IL-10…

… Mechanisms preserving the stability of the regulatory T cell (Treg) phenotype. Treg … due
to preferential binding of IL-2 through high expression of CD25 and higher activity of PP1 and …

… the control of miRNA function. Here, we review the mechanisms that modulate miRNA activity,
… T cells 102 and shown to be widespread in human cells 97 . Cleavage by Dicer has been …

… , are modulated by regulatory T cells (Tregs). Tregs play a fundamental role in immune …
high levels of miR‐210 result in a reduced suppressive activity of Tregs. Additionally, Treg …