[HTML][HTML] … acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: cell proliferation and …
R Scala, F Maqoud, M Angelelli, R Latorre, MG Perrone… - Cancers, 2019 - mdpi.com
… , whereas on osteoblasts, the inhibition of TRPV1 is linked to … be increased after the osteoblastic
differentiation of MC3T3-… , we use capsazepine to block TRPV1 channel because of the …
differentiation of MC3T3-… , we use capsazepine to block TRPV1 channel because of the …
[HTML][HTML] The Role of Ca2+-NFATc1 Signaling and Its Modulation on Osteoclastogenesis
JY Kang, N Kang, YM Yang, JH Hong… - International journal of …, 2020 - mdpi.com
… osteoblasts and suppressed LPS-induced osteoclast formation [39,43]. On the other hand, the
TRPV1 antagonist capsazepine inhibits … resorption activity of osteoclasts in OVX mice [44]. […
TRPV1 antagonist capsazepine inhibits … resorption activity of osteoclasts in OVX mice [44]. […
The role of TRPV channels in osteoporosis
N Liu, W Lu, X Dai, X Qu, C Zhu - Molecular Biology Reports, 2022 - Springer
… The TRPV1 channel, also known as a capsaicin receptor, … the effect of TRPV2 on osteoblast
differentiation. Importantly, a … overexpression and inhibits osteoclast differentiation and …
differentiation. Importantly, a … overexpression and inhibits osteoclast differentiation and …
[HTML][HTML] Inhibitory effect of Sirtuin6 (SIRT6) on osteogenic differentiation of bone marrow mesenchymal stem cells
F Xiao, Y Zhou, Y Liu, M Xie, G Guo - Medical science monitor …, 2019 - ncbi.nlm.nih.gov
… The levels of mRNAs related to osteoblast differentiation, such as OPN… Capsazepine is
TRPV1 ion channel antagonist. Previous studies have shown that capsazepine inhibits osteoclast …
TRPV1 ion channel antagonist. Previous studies have shown that capsazepine inhibits osteoclast …
[HTML][HTML] Bisphosphonates targeting ion channels and musculoskeletal effects
R Scala, F Maqoud, M Antonacci… - Frontiers in …, 2022 - frontiersin.org
… ) that are known to play a key role in osteoblast differentiation. … murine osteoblastic cells
with BPs inhibits the differentiation … the selective TRPV1-channel antagonist capsazepine. The …
with BPs inhibits the differentiation … the selective TRPV1-channel antagonist capsazepine. The …
The mechanosensory and mechanotransductive processes mediated by ion channels and the impact on bone metabolism: A systematic review
K Zhang, X Liu, L Wang, Z Liu, Q Yi, B Geng… - Archives of Biochemistry …, 2021 - Elsevier
… /PLC signal axis capsaicin attenuated the inhibition of PGE 2 … and OPN mechanically
enhanced osteoblast differentiation … subunits acting as ion channels in osteoclasts isolated from …
enhanced osteoblast differentiation … subunits acting as ion channels in osteoclasts isolated from …
Hydrogel-mediated release of TRPV1 modulators to fine tune osteoclastogenesis
… another observation that TRPV1 antagonist capsazepine inhibits osteoclast differentiation in
vitro … of new bone material by osteoblast differentiation and mineralization and resorption by …
vitro … of new bone material by osteoblast differentiation and mineralization and resorption by …
[HTML][HTML] The endocannabinoid/endovanilloid system in bone: from osteoporosis to osteosarcoma
… agents like capsazepine prevents bone loss, thereby enhancing osteoblast differentiation…
Taken together, the evidence from these studies suggests that TRPV1 deletion or inhibition …
Taken together, the evidence from these studies suggests that TRPV1 deletion or inhibition …
[HTML][HTML] Finely-tuned calcium oscillations in osteoclast differentiation and bone resorption
H Okada, K Okabe, S Tanaka - International Journal of Molecular …, 2020 - mdpi.com
… Cyclosporine A, which is an inhibitor of calcineurin, inhibited … TRP vanilloid 1 (TRPV1) was
identified as a capsaicin … through inhibition of osteoclast and osteoblast differentiation [82,88]. …
identified as a capsaicin … through inhibition of osteoclast and osteoblast differentiation [82,88]. …
[HTML][HTML] The role of TRPV1 in RA pathogenesis: worthy of attention
Y Qu, Y Fu, Y Liu, C Liu, B Xu, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
… Capsazepine, a TRPV1 ion channel antagonist, inhibits … In bone marrow-osteoblast co-cultures
and RANKL-generated osteoblast cultures, capsazepine inhibited osteoclast formation …
and RANKL-generated osteoblast cultures, capsazepine inhibited osteoclast formation …