Basal NAD (H) redox state permits hydrogen peroxide‐induced mesenteric artery dilatation

SM Raph, MM Dwenger, X Hu… - The Journal of …, 2023 - Wiley Online Library
… reduced nicotinamide adenine dinucleotideheart removal. Tissues were immediately excised
for arterial diameter … converts lactate to pyruvate and increases NADH levels in the cytosol. …

On the interdependence of ketone body oxidation, glycogen content, glycolysis and energy metabolism in the heart

AA Kadir, BJ Stubbs, CR Chong, H Lee… - The Journal of …, 2023 - Wiley Online Library
… period compared to heart perfused with buffer containing pyruvate + lactate + glucose + …
redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat

[HTML][HTML] Rat and mouse cardiomyocytes show subtle differences in creatine kinase expression and compartmentalization

J Branovets, K Soodla, M Vendelin, R Birkedal - Plos one, 2023 - journals.plos.org
pyruvate kinase; AK r , Adenylate kinase activity measured in … intracellular diffusion barriers
in the cytosol, which can group … 9, β-Nicotinamide adenine dinucleotide phosphate 9, P1P5-…

[HTML][HTML] Metabolic therapy of heart failure: Is there a future for B vitamins?

J Piquereau, SE Boitard, R Ventura-Clapier… - International Journal of …, 2021 - mdpi.com
cytosol by metabolizing glucose to pyruvate, which generates 2 ATP molecules. Pyruvate is
then either converted to lactate … and oxidized nicotinamide-adenine dinucleotide. Biochem. J. …

[HTML][HTML] Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

JR Tribble, A Otmani, S Sun, SA Ellis, G Cimaglia… - Redox biology, 2021 - Elsevier
Nicotinamide adenine dinucleotide (NAD) is a REDOX … in culture media as above (no
pyruvate, no glutamine) Prior to the … This RGC loss and nucleus shrinkage is robustly prevented …

Monitoring the skin NADH changes during ischaemia and reperfusion in humans

J Niziński, L Kamieniarz, P Filberek… - Journal of Medical …, 2020 - jms.ump.edu.pl
… chain, beta-oxidation, reduction of pyruvate to lactate, as well as … Nicotinamide adenine
dinucleotide exists in two forms: … Both are found in the cytosol, cellular organelles, nucleus and …

Advanced multinuclear magnetic resonance spectroscopy (MRS) imaging approaches for studying brain metabolism, neuroenergetics, and function

XH Zhu, M Lu, W Chen - Engineering in Medicine, 2019 - Elsevier
… as well as the nicotinamide adenine dinucleotide redox state. It … pyruvate molecules via
glycolysis in the cytosol. The majority of … converted to [3,3-d 2 ] lactate catalyzed by LDH. [3,3-d 2 ] …

Oxaloacetate protects rat liver from experimental warm ischemia/reperfusion injury by improving cellular energy metabolism

G Merlen, VA Raymond, S Cassim, P Lapierre… - Liver …, 2019 - journals.lww.com
nicotinamide adenine dinucleotide (NADH) ratio, a measure … to spontaneously decarboxylate
to pyruvate when in solution. … In the cytosol, the reduction of OAA to malate oxidizes NADH …

The bioenergetic and redox phenotype in human critical illness

HT McKenna - 2020 - discovery.ucl.ac.uk
… through simultaneous assessment of cellular bioenergetics, redox status and
microcirculatory … Assessing the utility of plasma redox measures as biomarkers ................................................... …

[HTML][HTML] Euterpe Oleracea Mart. (Açaí) Reduces Oxidative Stress and Improves Energetic Metabolism in Myocardial Ischemia-Reperfusion Injury in Rats

P Alegre, L Mathias, MA Lourenço… - Arquivos Brasileiros …, 2019 - SciELO Brasil
… , lactate dehydrogenase, pyruvate dehydrogenase and citrate … and migrates to the cell
nucleus, where it stimulates the … adenine dinucleotide and nicotinamide adenine dinucleotide