[HTML][HTML] Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue
A Rhoden, FW Friedrich, T Brandt, J Raabe… - Redox biology, 2021 - Elsevier
… Reduced nicotinamide adenine dinucleotide … lattice without sarcolemma and cytosol.
Trabeculae were exposed acutely to … pyruvate shuttling and instead reduction of pyruvate to …
Trabeculae were exposed acutely to … pyruvate shuttling and instead reduction of pyruvate to …
Malonyl CoA decarboxylase inhibition improves cardiac function post-myocardial infarction
W Wang, L Zhang, PK Battiprolu, A Fukushima… - JACC: Basic to …, 2019 - jacc.org
… high antioxidative action in cytosol, was significantly reduced … to the conversion of lactate
to pyruvate, thereby reducing … oxidation for preserving nicotinamide adenine dinucleotide …
to pyruvate, thereby reducing … oxidation for preserving nicotinamide adenine dinucleotide …
NAD+ homeostasis in renal health and disease
KM Ralto, EP Rhee, SM Parikh - Nature Reviews Nephrology, 2020 - nature.com
… for redox reactions in the cytosol and mitochondria. These … tubular epithelium, nicotinamide
adenine dinucleotide (NAD + ) … the cytosolic reduction of pyruvate to lactate regenerates NAD …
adenine dinucleotide (NAD + ) … the cytosolic reduction of pyruvate to lactate regenerates NAD …
[HTML][HTML] … concepts of ischemia-reperfusion injury to design renoprotective strategies and therapeutic interventions for normothermic ex vivo kidney perfusion
B Ogurlu, TL Hamelink, IM Van Tricht… - American Journal of …, 2024 - Elsevier
… lactate-to-pyruvate ratio is frequently used as a proxy for the cytosolic NADH-to-NAD + ratio.
Nicotinamide adenine dinucleotide … oxidative reactions in the cytosol and mitochondria. As a …
Nicotinamide adenine dinucleotide … oxidative reactions in the cytosol and mitochondria. As a …
A chronic low-dose magnesium L-lactate administration has a beneficial effect on the myocardium and the skeletal muscles
MM Pinto, H Dubouchaud, C Jouve… - Journal of physiology …, 2022 - Springer
… The transformation of L-lactate to pyruvate by the lactate … the release of cytochrome c into
the cytosol which then activates the process of … Oxidized nicotinamide adenine dinucleotide …
the cytosol which then activates the process of … Oxidized nicotinamide adenine dinucleotide …
Assessing kidney graft viability and its cells metabolism during machine perfusion
MI Bellini, F Tortorici, MI Amabile… - International Journal of …, 2021 - mdpi.com
… be reserved to mitochondrial nicotinamide adenine dinucleotide hydride (NADH) and …
pyruvate and NADH in the cytoplasm. In the absence of oxygen, pyruvate is reduced to lactate (or …
pyruvate and NADH in the cytoplasm. In the absence of oxygen, pyruvate is reduced to lactate (or …
Glucose utilization by the trained heart: the molecular mechanisms behind fuel choice
R Nogueira-Ferreira, D Moreira-Gonçalves, M Santos… - Glycolysis, 2024 - Elsevier
… of nicotinamide adenine dinucleotide (NADH) and flavin adenine … The pyruvate derived from
lactate oxidation can also … lactate shuttle mediates lactate exchanges between cytosol and …
lactate oxidation can also … lactate shuttle mediates lactate exchanges between cytosol and …
Lactate metabolism in human health and disease
X Li, Y Yang, B Zhang, X Lin, X Fu, Y An… - Signal transduction and …, 2022 - nature.com
… by oxidized nicotinamide adenine dinucleotides (NAD + or … Moreover, the oxidation of
lactate to pyruvate does not seem … lactate can mediate the transfer of HMGB1 from the nucleus …
lactate to pyruvate does not seem … lactate can mediate the transfer of HMGB1 from the nucleus …
[HTML][HTML] Mitochondrial complex I ROS production and redox signaling in hypoxia
CN Okoye, SA Koren, AP Wojtovich - Redox biology, 2023 - Elsevier
… I oxidizes nicotinamide adenine dinucleotide (… redox status of the UQ pool, which is the ratio
of UQH 2 to UQ serves as a sensor of ETC efficiency. Alterations in the UQ pool redox status …
of UQH 2 to UQ serves as a sensor of ETC efficiency. Alterations in the UQ pool redox status …
[HTML][HTML] In vivo dynamics of acidosis and oxidative stress in the acute phase of an ischemic stroke in a rodent model
IV Kelmanson, AG Shokhina, DA Kotova… - Redox Biology, 2021 - Elsevier
… nicotinamide adenine dinucleotide phosphate … the cytosol of neurons did not reach its
initial value. The intracellular NAD + /NADH ratio can be affected by changing the pyruvate/lactate …
initial value. The intracellular NAD + /NADH ratio can be affected by changing the pyruvate/lactate …