Hyperpolarized MR in cardiology: probing the heart of life
… production of nicotinamide adenine dinucleotide (NADH) … in the cytosol of the cell to generate
pyruvate and relatively small … , the pyruvate is reduced into lactate by the enzyme lactate …
pyruvate and relatively small … , the pyruvate is reduced into lactate by the enzyme lactate …
Monitoring neurochemistry in traumatic brain injury patients using microdialysis integrated with biosensors: a review
C Zimphango, FC Alimagham, KLH Carpenter… - Metabolites, 2022 - mdpi.com
… )-mediated conversion of pyruvate to lactate in the cytosol, as … information about the
cellular redox state in the region of … glucose, lactate, and pyruvate levels were measured from …
cellular redox state in the region of … glucose, lactate, and pyruvate levels were measured from …
Metabolism of the failing heart and the impact of SGLT2 inhibitors
A Garcia-Ropero, CG Santos-Gallego… - Expert opinion on …, 2019 - Taylor & Francis
… TCA cycle), nicotinamide adenine dinucleotide (NADH) and … less efficient than the oxidation
of pyruvate to form Acetyl-CoA, … This leads to accumulation of intermediates in the cytosol …
of pyruvate to form Acetyl-CoA, … This leads to accumulation of intermediates in the cytosol …
Decreased blood glucose and lactate: is a useful indicator of recovery ability in athletes?
… exercise, pyruvate is converted to lactate by lactate dehydrogenase (… of NADH to NAD +
in cytosol and reduction to NADH in the matrix. … NADH Nicotinamide adenine dinucleotide …
in cytosol and reduction to NADH in the matrix. … NADH Nicotinamide adenine dinucleotide …
Early decreased respiratory chain capacity in resuscitated experimental sepsis is a major contributor to lactate production
M von Seth, L Hillered, A Otterbeck, K Hanslin… - Shock, 2023 - journals.lww.com
… the heart and brain, which do not store glycogen but can use … Furthermore, analysis of lactate
the lactate-to-pyruvate ratio (… in our experiments suggest cell membrane injury or cell death …
the lactate-to-pyruvate ratio (… in our experiments suggest cell membrane injury or cell death …
Balancing NAD+ deficits with nicotinamide riboside: therapeutic possibilities and limitations
A Cercillieux, E Ciarlo, C Canto - Cellular and Molecular Life Sciences, 2022 - Springer
… -phosphorylated nicotinamide adenine dinucleotides is very … two NADH and two pyruvate
molecules that can either be … + levels, as free NAD + levels in the nucleus have been estimated …
molecules that can either be … + levels, as free NAD + levels in the nucleus have been estimated …
[13C]bicarbonate labelled from hyperpolarized [1-13C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state
… pyruvate is converted to C1 of lactate and alanine through … shuttle facilitate export to the
cytoplasm. Label exchange of … were respiration gated and cardiac triggered. For the PEPCK …
cytoplasm. Label exchange of … were respiration gated and cardiac triggered. For the PEPCK …
Murburn precepts for redox dynamics in glycolysis, Cori cycle and Warburg effect: Is lactate dehydrogenase a murzyme?
KM Manoj, V Nirusimhan, A Parashar, J Castin… - 2021 - osf.io
… of NADH for the reduction of pyruvate to lactate (the post-… why significant amount of lactate
formed in the cytoplasm of … of reduced nicotinamide adenine dinucleotide by superoxide …
formed in the cytoplasm of … of reduced nicotinamide adenine dinucleotide by superoxide …
SGLT2 inhibitors play a salutary role in heart failure via modulation of the mitochondrial function
Y Maejima - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
… Nicotinamide adenine dinucleotide (NADH), a reducing … However, NCX sets out to import Ca
2+ to the cytosol in the … due to increased conversion of pyruvate to lactate (58). Similarly, the …
2+ to the cytosol in the … due to increased conversion of pyruvate to lactate (58). Similarly, the …
Myocardial ketones metabolism in heart failure
… acids, carbohydrates (glucose and lactate), ketones, and amino … reduced in a nicotinamide
adenine dinucleotide-dependent … ketone oxidation is not clear, especially because pyruvate is …
adenine dinucleotide-dependent … ketone oxidation is not clear, especially because pyruvate is …