Impacts of intracellular lipid mobilisation on endothelial dysfunction

Y Huang - 2023 - ses.library.usyd.edu.au
… with the NFκB signalling pathway in the aorta endothelium [30]. … lead to modified biofunction
of lipids, such as alteration of … and Cav-1, were not altered after the knockdown of ORP2. The …

[HTML][HTML] Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans: a study protocol

KO Murray, M Berryman-Maciel, S Darvish… - Frontiers in …, 2022 - frontiersin.org
… Secondary outcomes include mtROS-mediated suppression of EDD, aortic stiffness as …
biopsy; the effect of altered circulating factors following MitoQ treatment on endothelial cell NO …

Endotoxinemia accelerates atherosclerosis through electrostatic charge–mediated monocyte adhesion

A Schumski, A Ortega-Gómez, K Wichapong, C Winter… - Circulation, 2021 - Am Heart Assoc
… a pronounced inflammatory response on uptake of modified lipids. With only limited numbers
of … N, Aortic root lesion size analyzed after hematoxylin and eosin staining. Quantification of …

The damaging duo: Obesity and excess dietary salt contribute to hypertension and cardiovascular disease

JC Watso, IS Fancher, DH Gomez… - Obesity …, 2023 - Wiley Online Library
… In the following sections, we will discuss how obesity … levels in various tissues including the
aorta, adipose, skeletal muscle, and … Conversely, multiple studies have identified an altered

Appropriate dose of ethanol exerts anti-senescence and anti-atherosclerosis protective effects by activating ALDH2

L Xue, W Zhu, F Yang, S Dai, Z Han, F Xu, P Guo… - … and biophysical …, 2019 - Elsevier
… the ascending aortas were embedded in Tissue Tek OCT embedding medium, after being
… To evaluate the formation of organic atherosclerotic plaques, the entire length of the aorta

[HTML][HTML] Development and application of endothelial cells derived from pluripotent stem cells in microphysiological systems models

CC Kennedy, EE Brown, NO Abutaleb… - Frontiers in …, 2021 - frontiersin.org
modified form of LDL, is often used to characterize ECs after … progressiva, Huntington's
disease, Kawasaki disease, type I … cardiomyopathy, calcified aortic valve disease, and hemophilia …

The status and challenges of replicating the mechanical properties of connective tissues using additive manufacturing

S Miramini, KL Fegan, NC Green, DM Espino… - Journal of the …, 2020 - Elsevier
… Here, the following case study tissues shall be used: arterial (coronary, aorta, and femoral), …
This review therefore aims to provide the following: (1) an overview of the biomechanics of CT…

Deep learning-based surrogate model for three-dimensional patient-specific computational fluid dynamics

P Du, X Zhu, JX Wang - Physics of Fluids, 2022 - pubs.aip.org
… of synthetic 3D aortas from a small set of original aorta shapes. … the learning rate is adaptively
changed based on the estimates … In this work, we made the following assumptions: (1) the …

[PDF][PDF] Cell monolayer deformation microscopy-a new method to measure the rheology of cell monolayers reveals mechanical fragility of the cell network in the …

AA Sutton, AJ Ehrlicher, CW Molter, A Amini, J Idicula… - Biophysical …, 2021 - cell.com
… in dishes 5 days after secondary differentiation. Preliminary … these mutant lines exhibited
significant alterations in force … However, regional heterogeneity of aortic smooth muscle …

[HTML][HTML] Measurement of normal retinal vascular pulse wave attenuation using modified photoplethysmography

A Abdul-Rahman, W Morgan, DY Yu - PloS one, 2020 - journals.plos.org
… The arterial diameter reached a maximum in mid systole, which is just after the period of
peak aortic pressure, whereas the increase in intraocular pressure during systole, lead to a …