[HTML][HTML] Captopril attenuates TAC-induced heart failure via inhibiting Wnt3a/β-catenin and Jak2/Stat3 pathways
Y Zhang, L Zhang, X Fan, W Yang, B Yu, J Kou… - Biomedicine & …, 2019 - Elsevier
… This study reveals another mechanism of captopril on heart failure caused by pressure … In
conclusion, Cap showed a protective effect on TAC-induced cardiac apoptosis, which could be …
conclusion, Cap showed a protective effect on TAC-induced cardiac apoptosis, which could be …
Angiotensin-converting enzyme inhibitors
R Ferrari, G Guardigli, B Bozkurt - The ESC Textbook of Heart …, 2023 - books.google.com
… the combination of low blood pressure, increased potassium level, … shared also by the rival
of captopril: Merck's longer-acting ACE … of blood volume and peripheral vascular resistance. …
of captopril: Merck's longer-acting ACE … of blood volume and peripheral vascular resistance. …
Hypotensive effect of captopril on deoxycorticosterone acetate-salt-induced hypertensive rat is associated with gut microbiota alteration
H Wu, TYC Lam, TF Shum, TY Tsai, J Chiou - Hypertension Research, 2022 - nature.com
… to elucidate the blood pressure-lowering effect of captopril on … Hypertension was induced for
14 weeks by subcutaneous injection … the central and peripheral nervous systems [42]. Since …
14 weeks by subcutaneous injection … the central and peripheral nervous systems [42]. Since …
ACE-Inhibitors in Hypertension: A historical perspective and current insights
S Cutrell, IS Alhomoud, A Mehta, AH Talasaz… - Current Hypertension …, 2023 - Springer
… and promoting deleterious effects on blood pressure. Parts of … After years of research and
development, captopril, the first … mortality, combined CHD, peripheral arterial disease, cancer, …
development, captopril, the first … mortality, combined CHD, peripheral arterial disease, cancer, …
[PDF][PDF] Toxin to medicine and bioisosterism in drug development: a study of the discovery and development of ACE inhibitors from snake venom
AR Oladipupo - Macedonian Pharmaceutical Bulletin, 2020 - bulletin.mfd.org.mk
… High blood pressure or hypertension, defined as blood pressure … SQ 14,225 was found to
be the most potent inhibitor of all the compounds tested and Squibb introduced it as captopril (…
be the most potent inhibitor of all the compounds tested and Squibb introduced it as captopril (…
[HTML][HTML] Mechanisms for the development of heart failure and improvement of cardiac function by angiotensin-converting enzyme inhibitors
SK Bhullar, AK Shah, NS Dhalla - Scripta Medica, 2022 - scindeks.ceon.rs
… effects for regulating the peripheral blood flow and blood … in cardiac output and fall in blood
pressure which result in the … beneficial effects of some of these agents including captopril, …
pressure which result in the … beneficial effects of some of these agents including captopril, …
Angiotensin-converting enzyme
F Arrighi, E Berrino, D Secci - Metalloenzymes, 2024 - Elsevier
… a pivotal role in the blood pressure (BP) regulation trough the … from the peripheral one,
ensured also by the blood-brain … zinc-chelating ability, produced captopril (SQ 14225), the first …
ensured also by the blood-brain … zinc-chelating ability, produced captopril (SQ 14225), the first …
Hypothalamic paraventricular nucleus augments baroreflex sensitivity, role of angiotensin II
… In support of our finding, it has been demonstrated that increasing arterial pressure using
Phe (iv), produced an increase in firing rate and reducing arterial pressure by hydralazine (iv) …
Phe (iv), produced an increase in firing rate and reducing arterial pressure by hydralazine (iv) …
Antihypertensive treatment during pregnancy induces long-term changes in gut microbiota and the behaviors of the attention deficit hyperactivity disorder offspring
HB Li, ML Xu, WJ Xia, YY Dong, B Peng, Q Su… - Toxicology and Applied …, 2024 - Elsevier
… a central area (50 × 50 cm) and a peripheral area (25 cm on each side). Animals were gently
placed in the center of … Captopril can reduce the blood pressure of the object and, under the …
placed in the center of … Captopril can reduce the blood pressure of the object and, under the …
Prescribed Systemic Drugs and Intraocular Pressure
J Zhang, PA Netland - Glaucoma Medical Therapy: Principles …, 2020 - books.google.com
… no demonstrable effect on the heart rate or blood pressure. 21 … by both central and peripheral
adrenergic mechanisms. 27, … Effect of oral captopril (SQ 14225) on intraocular pressure in …
adrenergic mechanisms. 27, … Effect of oral captopril (SQ 14225) on intraocular pressure in …