… Three deiodinase selenoenzymes control local availability of T3 to … Iodothyronine deiodinases
(DIO) are a family of … -spatial expression, regulation and function and exhibit different …

… the deiodinase-mediated (in-)activation of thyroid hormones, … ago as the second selenoprotein
family after glutathione … synthesis of DIOs and other crucial selenoenzymes (eg, GPX4, …

… thyroid gland and are involved in different processes, such as the formation and regulation
of THs (the iodothyronine deiodinases (DIO) family… more abundant selenoenzymes acting at …

… thyroid hormone action, and the cloning of the 3 deiodinase … and those encoding another
selenoenzyme, glutathione … selenodeiodinase family, as had been widely assumed (59). …

… of thyroid hormones, specifically by regulating deiodinases … and the action of zinc on the
metabolism of these hormones, … members of the ZIP family and 10 of ZnT family. In zinc excess …

… identified endogenous thyroid hormone metabolites, ie 3-iodothyronamine and 3-thyroacetic
acid. The concerted action of deiodinases 2 and 3 in regulation of local T3 availability is …

… families is variable, with a 12-year-old girl of the fourth family … : (a) selenoenzymes are
indispensable for thyroid hormone … thyroid hormone production through the deiodinases, the …

… by deiodination is the first step of thyroid hormone action and … but is also catalyzed within
target cells by a family of three … and release T3, which is available for the uptake into the …

… for the thyroid hormone (TH) axis (> 1000 hits for “selenium & … the 3 Sec-containing
deiodinases, and the pathogenetic role … that the 3 DIO selenoenzymes together control both local …

… These actions depend on provision of thyroid hormones in … (DIO1, DIO2, and DIO3,
respectively) are selenoenzymes with … Two families have been identified that carry heterozygous …