Nociceptive pulmonary‐cardiac reflexes: role of autonomic nervous system and hypertension.

OM Ruberti, DJ Feriani - Journal of Physiology, 2019 - search.ebscohost.com
… treatment with captopril (30 mg kg−1 day−1, PO) for 48 h in three SH rats. Captopril failed to
… of this study elucidate mechanisms involved in the reflex regulation of heart rate evoked by …

Both central sympathoexcitation and peripheral angiotensin II-dependent vasoconstriction contribute to hypertension development in immature heterozygous Ren-2 …

L Řezáčová, I Vaněčková, S Hojná, A Vavřínová… - Hypertension …, 2022 - nature.com
… baroreflex control of sympathetic vasomotor tone and heart rate… and RAS blockade by
pentolinium and captopril, we tried to … This is in good agreement with the mechanisms disclosed in …

Positive effects of angiotensin-converting enzyme (ACE) inhibitor, captopril, on pentylenetetrazole-induced epileptic seizures in mice

Y Tastemur, E Gumus, M Ergul, M Ulu, R Akkaya… - Tropical Journal of …, 2020 - ajol.info
… doses of captopril (p< 0.05). Conclusion: Captopril favorably improves epileptic seizure
parameters and acts against post-seizure neuronal injury in the hippocampus. Captopril may be …

[HTML][HTML] Should Renal Inflammation Be Targeted While Treating Hypertension?

S Chaudhari, GS Pham, CD Brooks, VQ Dinh… - Frontiers in …, 2022 - frontiersin.org
… These pathways augment heart rate, stroke volume, and total … Captopril is an ACE inhibitor
that effectively lowers blood … Another possible mechanism for activation of splenic nerve is via …

[HTML][HTML] Role of angiotensin II in chronic blood pressure control of heterozygous Ren-2 transgenic rats: Peripheral vasoconstriction versus central sympathoexcitation

L Řezáčová, S Hojna, L Kopkan, H Rauchova… - Biomedicine & …, 2019 - Elsevier
… Chronic icv administration of ACE inhibitor captopril … Blood pressure and heart rate (HR) were
recorded using a … Ang II pressor response by reflex attenuation of sympathetic nerve activity…

Angiotensin-converting enzyme inhibitors, asthma, and cough: relighting the torch

WJ Song, A Niimi - The Journal of Allergy and Clinical …, 2021 - jaci-inpractice.org
… In the late 1970s, captopril, one of the first orally active ACEIs, demonstrated clinical … reflex
hypersensitivity may interact and be overlapped but indeed have independent mechanisms

Angiotensin converting enzyme inhibition improves cerebrovascular control during exercise in male rats with heart failure

ALE Butenas, TD Colburn, DR Baumfalk, CJ Ade… - Respiratory physiology …, 2021 - Elsevier
effects of chronic (∼7 weeks) treatment with the angiotensin converting enzyme (ACE) inhibitor
Captopril in rats with heart … While heart rate (HR) and the arterial pressure waveform was …

Acute effects of sublingual nitroglycerin on cardiovagal and sympathetic baroreflex sensitivity

T Hamaoka, C Blaha, JC Luck… - American Journal …, 2021 - journals.physiology.org
… feedback mechanism that counteracts the change in BP (7), via regulating heart rate (HR) …
significant SNA excitation via a mechanism termed venous distention reflex (VDR) (42, 64). …

Severe impaired blood pressure control caused by baroreflex failure as a late sequela of neck irradiation

F Piani, M Landolfo, G Fiorini, S D'Addato… - Journal of …, 2020 - journals.lww.com
… BP and pulse rate were measured at 20 min intervals during … can blunt baroreceptor reflex
sensitivity decreasing carotid … [17] study revealed no statistical difference between captopril

An integrative pharmacokinetic-cardiovascular physiology modelling approach based on in vivo dog studies including five reference compounds

M Wallman, JM Borghardt, E Martel, N Pairet… - … of Pharmacological and …, 2022 - Elsevier
… of effects on arterial pressure and heart rate especially, rodent … Captopril was omitted from
this analysis due to its lack of … lowers TPR, with reflex tachycardia as a secondary effect. Rats …