Exercise and Parkinson's disease

X Xu, Z Fu, W Le - International review of neurobiology, 2019 - Elsevier
Dopamine and glutamate are important neurotransmitter that … that exercise could improve
dopamine neurotransmission … ideas for targeting treatment of neurodegenerative diseases. …

The benefits and mechanisms of exercise training for Parkinson's disease

YS Feng, SD Yang, ZX Tan, MM Wang, Y Xing, F Dong… - Life sciences, 2020 - Elsevier
… therapeutic effect of dopaminergic treatments gradually diminishes with time. Exercise training,
… multiple neurotransmitter system disorders, cellular dysfunction and neuroinflammation. …

BDNF as a promising therapeutic agent in Parkinson's disease

E Palasz, A Wysocka, A Gasiorowska… - International journal of …, 2020 - mdpi.com
… enhances the survival of dopaminergic neurons, improves dopaminergic neurotransmission
and motor performance. Pharmacological therapies of PD are symptom-targeting, and their …

… vs. continuous moderate-intensity aerobic exercise for improving neurotransmitter level and neurocognitive performance in individuals with Parkinson's disease

CL Tsai, TK Lin - Mental Health and Physical Activity, 2023 - Elsevier
… The target-onset time windows for calculating the mean N2 and P3 amplitudes were between
… The pathology of PD is marked by a neurotransmitter (eg, dopamine) deficiency. In animal …

Clinical applications of exercise in Parkinson's disease: what we need to know?

S Machado, D Teixeira, D Monteiro… - Expert Review of …, 2022 - Taylor & Francis
… survival of dopaminergic striatal neurons in patients with Parkinsons [… targeted at outcomes
related to individual disease … well as specific groups of neurotransmitters that are of particular …

Targeting neuroendocrine abnormalities in Parkinson's disease with exercise

NS Luthra, DD Christou, A Clow… - Frontiers in Neuroscience, 2023 - frontiersin.org
Parkinsons disease (PD) is a neurodegenerative disorder involving progressive loss of
nigrostriatal dopaminergic neurons. … Search for disease-modifying treatments targeting putative …

Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models

EK Crowley, YM Nolan, AM Sullivan - Progress in Neurobiology, 2019 - Elsevier
… PD is characterised by degeneration of dopaminergic … The consequent loss of the
neurotransmitter dopamine (DA) … of the lost dopaminergic neurotransmission, by administration of …

[HTML][HTML] Exercise-induced neuroprotection and recovery of motor function in animal models of Parkinson's disease

E Palasz, W Niewiadomski, A Gasiorowska… - Frontiers in …, 2019 - frontiersin.org
… neurotrophic factors, protection of dopamine neurons, and restoration of the equilibrium
between neurotransmitters such as dopamine and glutamate. Physical exercise may also lead to …

Vulnerabilities of aging and biological effects of physical activity provide new clues for interventions in Parkinson's disease

NI Bohnen - The Journals of Gerontology: Series A, 2020 - academic.oup.com
… of striatal dopaminergic losses (estimated 30% attenuation of this relationship). Therefore,
nigrostriatal dopaminergic neurotransmission could serve as a potential intervention target to …

Aerobic exercise improves motor dysfunction in Parkinson's model mice via differential regulation of striatal medium spiny neuron

Y Wang, L Wei, M Tan, Z Yang, B Gao, J Li, Y Liu… - Scientific Reports, 2024 - nature.com
… such as Alzheimer's disease (AD), Parkinsons disease (PD), … The target exercise intensity
was approximately 70–76% of … by the binding of neurotransmitters to their receptor proteins. …