Short chain fatty acids in human gut and metabolic health

EE Blaak, EE Canfora, S Theis, G Frost… - Beneficial …, 2020 - wageningenacademic.com
… (eg oral vs intragastric infusions vs colonic infusions vs gut microbial … Only a few gut bacteria
can use long-chain or complex … the effect of propionate on food intake in humans, there are …

[HTML][HTML] Dietary fatty acids in gut health: Absorption, metabolism and function

E Xu, C Chen, J Fu, L Zhu, J Shu, M Jin, Y Wang… - Animal Nutrition, 2021 - Elsevier
… mechanisms by which long-chain PUFA influence intestinal function. … dietary intake exerts
specific and localized effect over gastro-… the microbial content in human jejunum is needed to …

[HTML][HTML] Colonic medium-chain fatty acids act as a source of energy and for colon maintenance but are not utilized to acylate ghrelin

A Gregor, S Auernigg-Haselmaier, S Trajanoski… - Nutrients, 2021 - mdpi.com
… , the intake of MCFA through the modern human diet is less … relatively slow absorption of
long-chain fatty acids (LCFA) into … -Aldrich) either by infusion in the colon or by gavage using a …

[HTML][HTML] The short-chain fatty acid acetate in body weight control and insulin sensitivity

MA González Hernández, EE Canfora, JWE Jocken… - Nutrients, 2019 - mdpi.com
… acetate infusions have shown pronounced increments in gut … T2DM subjects, acetate
intravenous infusions (2.5 mmol per … that acetate might replace long chain fatty acids as preferred …

[HTML][HTML] Effects of intraduodenal administration of lauric acid and L-tryptophan, alone and combined, on gut hormones, pyloric pressures, and energy intake in healthy …

C McVeay, PCE Fitzgerald, SS Ullrich… - The American Journal of …, 2019 - Elsevier
… the infusions, energy intake from a standardized buffet meal … For example, in healthy humans
the intraduodenal infusion (… with C12 stimulating free fatty acid receptors and Trp activating …

Water intake increases mesenteric lymph flow and the total flux of albumin, long-chain fatty acids, and IL-22 in rats: new concept of absorption in jejunum

S Nagashio, K Ajima, D Maejima… - … -Gastrointestinal …, 2019 - journals.physiology.org
infusion of PSS was stopped during the experiments, because we had confirmed with preliminary
experiments that the intravenous infusion of … with the anti-human/mouse RORγt Ab and …

Intestinal delivery in a long-chain fatty acid formulation enables lymphatic transport and systemic exposure of orlistat

G Lee, S Han, Z Lu, J Hong, ARJ Phillips… - International Journal of …, 2021 - Elsevier
intestinal administration in lipid formulations (LFs). The effect of lipid type, lipid dose, orlistat
dose, and infusion time … For example, in healthy volunteers and human patients, the plasma …

Small amounts of dietary medium-chain fatty acids protect against insulin resistance during caloric excess in humans

AM Lundsgaard, AM Fritzen, KA Sjøberg, M Kleinert… - Diabetes, 2021 - Am Diabetes Assoc
… fraction of the saturated long-chain fatty acids (LCFAs). A … vein in their nonesterified form
after intestinal absorption (6,7)… so tracer infusion followed the variable glucose infusion rate (…

Effects of intraduodenal coadministration of lauric acid and leucine on gut motility, plasma cholecystokinin, and energy intake in healthy men

C McVeay, RE Steinert… - American Journal …, 2020 - journals.physiology.org
… In our recent study, intraduodenal infusion of a combination of C12 … Effects of intraduodenal
fatty acids on appetite, antropyloroduodenal motility, and plasma CCK and GLP-1 in humans

[HTML][HTML] Long-chain monounsaturated fatty acids improve endothelial function with altering microbial flora

R Tsutsumi, Y Yamasaki, J Takeo, H Miyahara… - Translational …, 2021 - Elsevier
… in humans, we used Trimethylamine-N-oxide (TMAO) in humans as an indicator of the gut
to the amount ingested by Japanese people every day and the dietary intake on the subjects …