Sensing Intra‐ and Extra‐Cellular Ca2+ in the Islet of Langerhans

W Huang, T Wu, C Xie, CK Rayner… - Advanced Functional …, 2022 - Wiley Online Library
microscopy images of human and mouse pancreatic islets … of biphasic insulin secretion of
pancreatic islets, where a … β cells by selectively transporting cations and small molecules. [ 42 ] …

Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae

N Faraj, BHP Duinkerken, EC Carroll… - FEBS …, 2022 - Wiley Online Library
… larval zebrafish pancreas in the context of islets of Langerhans and … a SPIM microscope of
membrane-localized mScarlet under … Channelrhodopsin-2 (ChR2) is a light-responsive cation

Pancreatic Antioxidative Defense and Heat Shock Proteins Prevent Islet of Langerhans Cell Death After Chronic Oral Exposure to Cadmium LOAEL Dose

D Moroni-González, VE Sarmiento-Ortega… - … Trace Element Research, 2024 - Springer
… proteins, zinc-iron permease, and organic cation transporters as reviewed in [10, 33].
Although the pancreas, and particularly islets of Langerhans, are not the primary target tissues of …

In vitro generation of peri-islet basement membrane-like structures

J Santini-González, JA Simonovich, R Castro-Gutiérrez… - Biomaterials, 2021 - Elsevier
… blot, and transmission electron microscopy. The ECM coatings … As laminin network
polymerization is divalent cation … μm thickness human pancreas tissue slice (islet location

[HTML][HTML] Simultaneous measurement of changes in mitochondrial and endoplasmic reticulum free calcium in pancreatic beta cells

S Jeyarajan, IX Zhang, P Arvan, SI Lentz, LS Satin - Biosensors, 2023 - mdpi.com
location in the cell of the Ca 2+ components SERCA, IP3 and RyR channels, MCU and NCLX.
To determine whether each sensor was correctly localized to its … probes are localized to …

[HTML][HTML] Unravelling innervation of pancreatic islets

RF Hampton, M Jimenez-Gonzalez, SA Stanley - Diabetologia, 2022 - Springer
… , rodents and humans, by light and electron microscopy after immunolabelling for choline …
[40], as well as transient receptor potential cation channel subfamily V member 1 (TRPV1, …

The Importance of Intra-Islet Communication in the Function and Plasticity of the Islets of Langerhans during Health and Diabetes

TG Hill, DJ Hill - International Journal of Molecular Sciences, 2024 - mdpi.com
… Monoamines in the pancreatic islets of the mouse. Subcellular localization of 5-hydroxytryptamine
by electron microscopic autoradiography. Diabetologia 1971, 7, 339–348. https://doi.…

New Fluorescent Dye for the Detection of Zn2+ in Living Cells and Fixed Sections of the Rat Pancreas

A Krinochkin, M Valieva, E Starnovskaya… - Journal of …, 2024 - Springer
… with cations are in a bound state. The high binding constant of compound 12 to Zn 2… cation
allows it to be used for the accurate localization of pancreatic beta cells (islets of Langerhans

Nutrient metabolism, subcellular redox state, and oxidative stress in pancreatic islets and β-cells

LP Roma, JC Jonas - Journal of molecular biology, 2020 - Elsevier
Insulin-secreting pancreatic β-cells play a critical role in blood glucose homeostasis and the
development of type 2 diabetes (T2D) in the context of insulin resistance. Based on data …

A 3D atlas of the dynamic and regional variation of pancreatic innervation in diabetes

A Alvarsson, M Jimenez-Gonzalez, R Li, C Rosselot… - Science …, 2020 - science.org
location of internal structures (8). Until now, laborious serial sectioning and reconstruction
have been needed to deliver information about islet anatomy throughout the pancreas. … cation