Beneficial changes in rat vascular endocannabinoid system in primary hypertension and under treatment with chronic inhibition of fatty acid amide hydrolase by …

M Baranowska-Kuczko, H Kozłowska, M Kloza… - International Journal of …, 2021 - mdpi.com
endothelium-intact vessels: resistance (mesenteric G3 … against the cannabinoid CB 1 receptor
[1:1000; rabbit Anti-CB 1 … anandamide), induce relaxation of the mesenteric arteries via CB …

Characterization of Cannabinoid Receptors in the Peripheral Nervous System and in the Gastrointestinal Tract of Mammals of Veterinary Interest

G Galiazzo - 2020 - amsdottorato.unibo.it
… The first chapter focuses on the ECS and its components. The … PPARγ is also present in
endothelial and vascular smooth … was raised in rabbit, as were all the anti -cannabinoid receptor …

Role of the endocannabinoidome in human and mouse atherosclerosis

F Piscitelli, C Silvestri - Current Pharmaceutical Design, 2019 - ingentaconnect.com
… of marijuana/cannabis and its major psychoactive component… inflammatory factors in a rabbit
atherosclerosis model [132]. … and endothelial wound healing through induction of vascular

Cannabinoids—A New Perspective in Adjuvant Therapy for Pulmonary Hypertension

A Krzyżewska, M Baranowska-Kuczko… - International Journal of …, 2021 - mdpi.com
… ] hypothesized that cannabinoids could become an element of … was previously shown to relax
rabbit pulmonary arteries [52]. … the vascular endothelium reduces the relaxation induced by …

Capsaicin Causes Vasorelaxation of Rat Aorta through Blocking of L-type Ca2+ Channels and Activation of CB1 Receptors

F Andrade, C Rangel-Sandoval… - Molecules, 2020 - mdpi.com
… of TRPV1 mainly in the endothelial and smooth muscle cells … endothelial cell layer in an aortic
ring with polyclonal rabbit … of the aorta and mesenteric arteries leads to activation of BK Ca …

Cannabidiol ameliorates monocrotaline-induced pulmonary hypertension in rats

O Sadowska, M Baranowska-Kuczko… - International Journal of …, 2020 - mdpi.com
… MCT-induced PH in rats by improving endothelial efficiency … CBD causes relaxation of human
mesenteric arteries [4] and … We confirmed that similarly to the lungs of rabbits [34], rats [35…

The endocannabinoid system and cannabidiol: Past, present, and prospective for cardiovascular diseases

M Rabino, S Mallia, E Castiglioni, D Rovina… - Pharmaceuticals, 2021 - mdpi.com
… of perfused isolated rat mesenteric arterial beds. The study … primary human coronary artery
endothelial cells induced ROS … in cardiac contractility in a rabbit animal model of SC [119]. …

Cannabinoids in arterial, pulmonary and portal hypertension–mechanisms of action and potential therapeutic significance

B Malinowska, M Toczek… - British Journal of …, 2019 - Wiley Online Library
… This article is part of a themed section on 8 th European … aorta and coronary vessels (but
not mesenteric artery) in older … Ang II may stimulate rapid endothelial release of eCBs, leading …

Naturally occurring cannabinoids and their role in modulation of cardiovascular health

E Karimian Azari, A Kerrigan… - Journal of Dietary …, 2020 - Taylor & Francis
… Overactivation of components of the ECS has been … In vascular endothelial cells, the CB1
receptor is responsible … of anandamide induced vasorelaxation in mesenteric arteries was …

The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease

A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
… in blood vessels (GPR18 was deorphanised as the endothelial … In rabbits, CBD administered
before the experimentally … isolated mesenteric arteries (but not in aorta and femoral arteries) …