Role of B cells in multiple sclerosis and related disorders

G Comi, A Bar‐Or, H Lassmann, A Uccelli… - Annals of …, 2021 - Wiley Online Library
… T cells are widely considered to be major contributors to inflammatory demyelination in
MS, growing evidence suggests a significant role for B cells … thought to underlie B-cell–mediated …

[HTML][HTML] Impact of B cells to the pathophysiology of multiple sclerosis

BM Arneth - Journal of Neuroinflammation, 2019 - Springer
… This review aimed to determine the role of B cells in MS development… evidence that describes
how B cells affect MS development. Articles that examined the association between B cells

Role of B cells and antibodies in multiple sclerosis

P Wanleenuwat, P Iwanowski - Multiple sclerosis and related disorders, 2019 - Elsevier
cells are widely known to be of major contribution to inflammatory demyelination in MS,
growing evidence suggests a significant role of B cells … T-cell activity and B-cell expression of …

[HTML][HTML] The role of B cells in primary progressive multiple sclerosis

JP Holloman, RC Axtell, NL Monson, GF Wu - Frontiers in Neurology, 2021 - frontiersin.org
… in primary progressive multiple sclerosis (PPMS) via CD20-targeted depletion implicates B
cells as … This review explores the possible mechanisms by which B cells contribute to disease …

[HTML][HTML] The role of B cells and antibodies in multiple sclerosis, neuromyelitis optica, and related disorders

S Häusser-Kinzel, MS Weber - Frontiers in immunology, 2019 - frontiersin.org
… summarize pro-inflammatory B cell properties in these three … on the emerging concept that
B cells or B cell subsets may exert … B cell-directed therapeutic approaches in multiple sclerosis

Contribution of B cells to cortical damage in multiple sclerosis

P Bhargava, HP Hartung, PA Calabresi - Brain, 2022 - academic.oup.com
… in progressive multiple sclerosis, has led to novel hypotheses regarding the role of B cells
in mediating cortical pathology. In this paper, we describe the emerging role of B cells in …

[HTML][HTML] B and T cells driving multiple sclerosis: identity, mechanisms and potential triggers

J Van Langelaar, L Rijvers, J Smolders… - Frontiers in …, 2020 - frontiersin.org
role for B cells in MS patients. The results from this treatment put forward T-cell activation rather
than antibody production by B cells as … interaction provokes both B and T cells to infiltrate …

B cells in multiple sclerosis—from targeted depletion to immune reconstitution therapies

MT Cencioni, M Mattoscio, R Magliozzi… - Nature Reviews …, 2021 - nature.com
evidence indicates the involvement of B cells in the pathogenesis of multiple sclerosis (MS),
but their precise roles are … functions of B cells and the main mechanisms through which …

[HTML][HTML] B cells in multiple sclerosis and virus-induced neuroinflammation

R Chunder, V Schropp, S Kuerten - Frontiers in neurology, 2020 - frontiersin.org
… Indeed, advancing our knowledge on the role of B cells in neuroinflammation would also
allow us to … with a focus on the involvement of B cells in MS and viral infections of the CNS. …

B cells in the CNS at postmortem are associated with worse outcome and cell types in multiple sclerosis

M Moccia, L Haider, A Eshaghi… - Neurology …, 2021 - AAN Enterprises
B cells in postmortem progressive multiple sclerosis (MS) brains. … B cells with anti-CD20
antibodies has emerged as highly effective therapeutic mechanism in multiple sclerosis (MS). …