… There is insufficient evidence in stable COPD to determine whether treatment step-down
can be safe and/or without reducing patient benefits; treatment step-down should only be …

… function, tiotropium did so to a greater extent than salmeterol. … a large proportion of total
COPD burden on the healthcare … reducing COPD exacerbations and treatment of stable COPD …

… Conclusion: Tiotropium bromide combined with high dose of salmeterol xinafoate (… function
of patients with moderate to severe stable COPD. Keywords: Tiotropium bromide, salmeterol …

… Maintenance bronchodilator therapy is key to the management of stable COPD, which aims
to … propionate/salmeterol at improving lung function in patients with moderate to severe …

… We examined the effect of tiotropium/olodaterol 5/5 µg versus tiotropium 5 µg on trough
FEV 1 response, St. George’s Respiratory Questionnaire (SGRQ) total score and Transition …

… of COPD. Across a wide range of people with COPD, we found that treatment with
tiotropium/olodaterol reduced the risk of a CID compared with tiotropium alone. This includes in …

… antagonist tiotropium and the long… the effects of a fixed-dose combination (FDC) of
tiotropium/olodaterol (delivered via Respimat ® ) on physical functioning in patients with stable …

… improvement in lung function [25]. In addition, while MF showed no notable differences in
lung function and asthma symptom control versus FLU in patients with severe persistent …

… salmeterol [Citation13]. Additionally, in these symptomatic, low exacerbation-risk patients
with COPD, dual bronchodilation provided early and sustained improvements in lung function …

… and it has also demonstrated superior lung function benefits compared with tiotropium [17]. …
in symptomatic patients with COPD, before a high exacerbation risk develops. In addition, …