… to tiotropium monotherapy in patients with higher levels of blood eosinophils [Citation51,Citation52].
In the IMPACT … /LAMA and this effect was even greater in patients having ≥150 cells/…

… with arformoterol via nebulizer than dry powder salmeterol in a relatively small crossover trial…
with FEV 1 < 50% predicted and suboptimal peak flow (sPIFR) compared with tiotropium via …

… , fluticasone propionate/salmeterol was associated with a … true impact on the airway microbiome
or the natural evolution of the airway microbiome over time in patients with stable COPD. …

… In 511 moderate to severe symptomatic stable COPD, the Glycopyrrolate Effect on
syMptoms and lung function study (GEM3), a double-blind, multicenter, parallel-group study, …

… /salmeterol in chronic obstructive pulmonary disease (COPD). Methods Patients with COPD
and ≥1 … . Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in …

… There is uncertainty regarding whether patients with stable COPD … Tiotropium in combination
with placebo, salmeterol, or … of budesonide/formoterol added to tiotropium in patients with …

… with tiotropium, indicating a more significant treatment effect. … a direct switch from tiotropium
or salmeterol/fluticasone … in increasing lung function (trough FEV 1 ) in stable COPD patients. …

… treated with tiotropium significantly improved lung function without … patients with stable
COPD [Citation69]. However, this information is not valid for less symptomatic patients or patients …

… in patients with severe COPD treated with fluticasone propionate (an ICS) and salmeterol
[long-… of therapy with either tiotropium or placebo in patients with COPD who were permitted to …

… The three LAMA/LABA FDCs administered to COPD patients show similar effects and safety,
… combination therapy may improve cardiac function in COPD patients with heart failure [28]. …