New insights into exogenous surfactant as a carrier of pulmonary therapeutics

B Baer, LMP Souza, AS Pimentel… - Biochemical …, 2019 - Elsevier
… The origins of exogenous surfactant therapy lie in the discovery … the basics as they relate
to exogenous surfactant therapy. … to overcome current and future therapeutic challenges. …

The COVID-19 pandemic: a target for surfactant therapy?

RAW Veldhuizen, YY Zuo, NO Petersen… - Expert review of …, 2021 - Taylor & Francis
… relate to the potential of exogenous surfactant therapy for COVID-19 … exogenous surfactant
administration remains primarily directed by trial and error and needs to be optimized in future

Exogenous surfactant therapy

KS Gautham, RF Soll - … Assisted Ventilation of the Neonate-E …, 2021 - books.google.com
surfactant with protein components. • In preterm infants with respiratory distress syndrome,
administration of exogenous surfactant therapy … consensus opinion for future research steps. …

[HTML][HTML] Surfactant replacement therapy: from biological basis to current clinical practice

R Hentschel, K Bohlin, A van Kaam, H Fuchs… - Pediatric …, 2020 - nature.com
… the most promising aims for future development. Scientists have … Administration of exogenous
surfactant to preterm infants … , surfactant therapy has become the standard therapy of …

Can we balance early exogenous surfactant therapy and non-invasive respiratory support to optimise outcomes in extremely preterm infants? A nuanced review of the …

K Glaser, NA Bamat, CJ Wright - Archives of Disease in Childhood-Fetal …, 2023 - fn.bmj.com
exogenous surfactant therapy in these infants. Finally, we argue that less invasive modes of
surfactant administration … approach in combining CPAP/NIV and early surfactant. Beneficial …

Exogenous pulmonary surfactant: A review focused on adjunctive therapy for severe acute respiratory syndrome coronavirus 2 including SP-A and SP-D as added …

A Ghati, P Dam, D Tasdemir, A Kati, H Sellami… - Current opinion in …, 2021 - Elsevier
future development of optimal surfactant delivery techniques and … exogenous surfactant
therapy in severe lung diseases. A clinical trial on exogenous surfactant administration therapy (…

[HTML][HTML] Surfactant therapies for pediatric and neonatal ARDS: ESPNIC expert consensus opinion for future research steps

D De Luca, P Cogo, MC Kneyber, P Biban, MG Semple… - Critical Care, 2021 - Springer
… the future, we can imagine an even more individualized therapy … type: the surfactant adsorption
test [63,64,65] and the surfactant … In time, our knowledge about exogenous surfactant has …

[HTML][HTML] Pulmonary surfactant in adult ARDS: current perspectives and future directions

A Dushianthan, MPW Grocott, GS Murugan… - Diagnostics, 2023 - mdpi.com
… While it is possible to claim that exogenous surfactant is an ineffective treatment strategy
for … (1) Which patients require surfactant therapy and what type of surfactant is indicated? (2) …

[HTML][HTML] Surfactant therapy for COVID-19 related ARDS: a retrospective case–control pilot study

S Piva, RM DiBlasi, AE Slee, AH Jobe, AM Roccaro… - Respiratory …, 2021 - Springer
Surfactant administration did not cause acute decompensation… This study supports the future
performance of randomized … Thus, our data suggest that exogenous surfactant installation …

Use of exogenous pulmonary surfactant in acute respiratory distress syndrome (ARDS): Role in SARS-CoV-2-related lung injury

F Cattel, S Giordano, C Bertiond, T Lupia… - Respiratory physiology …, 2021 - Elsevier
… COVID-19 causes lung damage and ARDS, so beneficial effects of surfactant therapy in
COVID-19-associated ARDS patients are conceivable, especially when applied early in the …