[HTML][HTML] The Hsp70/J-protein machinery of the African trypanosome, Trypanosoma brucei
… of the neglected tropical disease African trypanosomiasis, Trypanosoma brucei, possesses
an … The completion of the genome sequence for T. b. brucei in 2005 and the subsequent …
an … The completion of the genome sequence for T. b. brucei in 2005 and the subsequent …
African trypanosome strategies for conquering new hosts and territories: the end of monophyly?
… Trypanosoma brucei parasites are the causative agents of African trypanosomiasis in humans,
as well as surra, … Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: …
as well as surra, … Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: …
African trypanosomes
… Trypanosoma brucei also possesses a uniquely evolved … Trypanosoma brucei possesses
~2500 VSG genes or … pathways at a genome-wide scale in trypanosomes. For example, in the …
~2500 VSG genes or … pathways at a genome-wide scale in trypanosomes. For example, in the …
Signatures of hybridization in Trypanosoma brucei
C Kay, L Peacock, TA Williams, W Gibson - PLoS pathogens, 2022 - journals.plos.org
… brucei and then applied these insights to genomic analysis of field-collected isolates to
identify signatures of past genetic exchange. Genomes of two parental and four hybrid progeny …
identify signatures of past genetic exchange. Genomes of two parental and four hybrid progeny …
[HTML][HTML] Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome
… Antigenic variation has evolved remarkable mechanistic complexity in Trypanosoma brucei,
… to direct VSG switching in Trypanosoma brucei. (a) Three DNA lesions predicted to form …
… to direct VSG switching in Trypanosoma brucei. (a) Three DNA lesions predicted to form …
Assembly and annotation of the mitochondrial minicircle genome of a differentiation-competent strain of Trypanosoma brucei
S Cooper, ES Wadsworth, T Ochsenreiter… - Nucleic acids …, 2019 - academic.oup.com
… Trypanosoma brucei, the kinetoplast is a chain mail-like network of two types of interlocked
DNA molecules: a few dozen ∼23-kb maxicircles (homologs of the mitochondrial genome of …
DNA molecules: a few dozen ∼23-kb maxicircles (homologs of the mitochondrial genome of …
In vitro culture of freshly isolated Trypanosoma brucei brucei bloodstream forms results in gene copy-number changes
J Mulindwa, G Ssentamu, E Matovu… - PLoS neglected …, 2021 - journals.plos.org
… The Trypanosoma brucei genome consists of eleven megabase-length chromosomes, …
DNA contents vary up to 30% between T. brucei isolates [7]. Although some of this can be …
DNA contents vary up to 30% between T. brucei isolates [7]. Although some of this can be …
Genome-scale RNAi screens in African trypanosomes
D Horn - Trends in Parasitology, 2022 - cell.com
… assessed in massive parallel, genome-scale format in African trypanosomes. A substantial
advantage in … A nucleoside transporter from Trypanosoma brucei involved in drug resistance. …
advantage in … A nucleoside transporter from Trypanosoma brucei involved in drug resistance. …
Persistent DNA damage foci and DNA replication with a broken chromosome in the African trypanosome
L Glover, CA Marques, O Suska, D Horn - MBio, 2019 - Am Soc Microbiol
… Damaged DNA … DNA breaks, and the resulting rearrangements, are advantageous, however.
For example, antigenic variation in the parasitic African trypanosome, Trypanosoma brucei, …
For example, antigenic variation in the parasitic African trypanosome, Trypanosoma brucei, …
Trypanosoma brucei gambiense Group 2: the unusual suspect
…, S Herder, S Ravel, P Solano, T De Meeus - Trends in …, 2019 - cell.com
… Trypanosoma brucei causes human African trypanosomiasis (HAT). Three subspecies were
described: T. b… - and animal-infective African trypanosomes are morphologically identical, T. …
described: T. b… - and animal-infective African trypanosomes are morphologically identical, T. …