[HTML][HTML] HIF-1-induced hsa-miR-429: understanding its direct targets as the key to developing cancer diagnostics and therapies

S Bartoszewska, J Sławski, JF Collawn… - Cancers, 2023 - mdpi.com
… The master regulators of these cellular activities are hypoxia-inducible factors (HIFs) that
during … Thus, hsa-miR-429 regulates the transitional switch between HIF-1-, HIF-2- and HIF-3-…

Hypoxia-inducible Factors—Their Regulation and Function in Neural Tissue

TI Baranich, AS Voronkova, PL Anufriev, AV Brydun… - Human Physiology, 2020 - Springer
… has been shown to mediate the transition from HIF1α to HIF3α in long-term … that miR-429
can regulate changes in HIF factor activity in long-term hypoxia by attenuating HIF1 expression. …

[HTML][HTML] MiR-429 regulates blood− spinal cord barrier permeability by targeting Krüppel-like factor 6

R Sun, L Ge, Y Cao, W Wu, Y Wu, H Zhu, J Li… - Biochemical and …, 2020 - Elsevier
… cell apoptosis via bcl-2 [6], and is also hypoxia-inducible, regulating hypoxia-inducible factor-
… that miR-429 mediates the expression of TJ proteins by targeting KLF6, thus regulating

MicroRNA-429/Cxcl1 axis protective against oxygen glucose deprivation/reoxygenation-induced injury in brain microvascular endothelial cells

J Leng, W Liu, L Li, FY Wei, M Tian, HM Liu… - Dose …, 2020 - journals.sagepub.com
miR-429 directly targets Cxcl1 and negatively regulates Cxcl1 … MiR-429, as an important
member of the miR-200 family, has been reported to be induced by hypoxia-inducible factor , …

[HTML][HTML] Upregulated microRNA-429 confers endometrial stromal cell dysfunction by targeting HIF1AN and regulating the HIF1A/VEGF pathway

R Zheng, Y Liu, Y Lei, Y Yue - Open Medicine, 2023 - degruyter.com
… confirmed that miR-429 targeted hypoxia-inducible factor 1 … miR-429 functions and molecular
mechanisms in regulating … that miR-429 might mediate ESC phenotypes by regulating

MiR-429/200a/200b negatively regulate Notch1 signaling pathway to suppress CoCl2-induced apoptosis in PC12 cells

C Yang, X Zhang, H Yin, Z Du, Z Yang - Toxicology in vitro, 2020 - Elsevier
… to human health. Notch1 signaling pathway and three members of miR-200 family, miR-429, …
Real-time polymerase chain reaction (RT-PCR) showed that expressions of miR-429/200a/…

[HTML][HTML] Primary endothelial cell–specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia

R Bartoszewski, A Moszyńska, M Serocki… - The FASEB …, 2019 - ncbi.nlm.nih.gov
… Furthermore, using 4 genome-wide mRNA expression arrays of HUVECs during … to be
regulated exclusively by HIF-1 or HIF-2, the largest number of genes appeared to be regulated by …

[HTML][HTML] Hypoxia-inducible factor-1: a novel therapeutic target for the management of cancer, drug resistance, and cancer-related pain

BP Bui, PL Nguyen, K Lee, J Cho - Cancers, 2022 - mdpi.com
… One of the important mechanisms is the activation of hypoxia-inducible factor-1 (HIF-1), as
a key transcription factor that regulates the transcription of many genes responsible for the …

miR-429 and miR-424-5p inhibit cell proliferation and Ca2+ influx by downregulating CaSR in pulmonary artery smooth muscle cells

C Li, F Qin, M Xue, Y Lei, F Hu, H Xu… - … of Physiology-Cell …, 2019 - journals.physiology.org
regulating hypoxia-inducible factor-1A expression in human endothelial cells (3, 17). The
expression of miR-429 … studies have indicated that rno-miR-429 level is decreased on rat PAH …

[HTML][HTML] Estradiol mediates the interaction of LINC01541 and miR-429 to promote angiogenesis of G1/G2 endometrioid adenocarcinoma in-vitro: A pilot study

D Qiao, X Qin, H Yang, X Liu, L Liu, S Liu… - Frontiers in Oncology, 2022 - frontiersin.org
… of VEGFA by regulating the expression of LINC01541 and miR-429 in … MiR-429 has been
shown to increase the expression of … of hypoxia-inducible factor (HIF-1α) in human amniotic …