SChLAP1 promotes prostate cancer development through interacting with EZH2 to mediate promoter methylation modification of multiple miRNAs of chromosome 5 …

K Huang, Y Tang - Cell Death & Disease, 2021 - nature.com
microRNA prostate cancer cells were predicted by informatics and confirmed by qRT-PCR.
SChLAP1-interacting … , histone modification was also reported to affect miRNA expression in …

Epigenetic regulation of prostate cancer: the theories and the clinical implications

Y Liao, K Xu - Asian journal of andrology, 2019 - journals.lww.com
… highlighting particular epigenetic modifications as diagnostic … controlling the dynamic
interaction between histone and DNA… Just like the abovementioned cases, multiple miRNAs show …

MicroRNAs as epigenetic determinants of treatment response and potential therapeutic targets in prostate cancer

V Doldi, R El Bezawy, N Zaffaroni - Cancers, 2021 - mdpi.com
Epigenetic modifications and aberrant miRNA expression can … facilitating the development
and progression of cancer [62]. … physical interaction almost completely abrogated miRNA-…

Epigenetic and epitranscriptomic control in prostate cancer

J López, AM Añazco-Guenkova, Ó Monteagudo-García… - Genes, 2022 - mdpi.com
… In conclusion, all this evidence highlights that epigenetic alterations are commonly
associated with PCa and, most importantly, can be used to stratify patient risk, predict clinical …

[HTML][HTML] Epigenetic modulations and lineage plasticity in advanced prostate cancer

R Ge, Z Wang, R Montironi, Z Jiang, M Cheng… - Annals of …, 2020 - Elsevier
cancer and the interaction between epigenetic and genetic … with cancer progression 46 and
can be inhibited by microRNA-101. … of the epigenetic alterations in human prostate cancers

Integrative epigenomics of prostate cancer

M Peter, S Kamdar, B Bapat - Computational epigenetics and diseases, 2019 - Elsevier
… -negative cancers exhibit unique microRNA expression and … characterization of epigenetic
and genetic interaction via … the role of epigenetic changes in prostate cancer. Although many …

Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
… proven interactions between epigenetic modifications and miRNAs … In prostate cancer,
HDAC1 is targeted by miR-34b (… between epigenetic alteration of miRNAs and miRNA-mediated …

Integrative analysis of MicroRNA and gene interactions for revealing candidate signatures in prostate cancer

J Wei, Y Yin, Q Deng, J Zhou, Y Wang, G Yin… - Frontiers in …, 2020 - frontiersin.org
… and miRNAs of prostate cancer in TCGA database as well as the WGCNA approach, we
identified three genes and four miRNAs that were tightly correlated with prostate cancer and …

Recent advances in epigenetic biomarkers and epigenetic targeting in prostate cancer

A Kumaraswamy, KRW Leng, TC Westbrook, JA Yates… - European urology, 2021 - Elsevier
… Although there are many different histone modifications, this … of microRNA family miR-29 that
leads to reduced TET2 mRNA [23]. … -protein interactions of specific histone demethylases or …

Epigenetic reprogramming during prostate cancer progression: a perspective from development

S Goel, V Bhatia, T Biswas, B Ateeq - Seminars in cancer biology, 2022 - Elsevier
… chemical modifications on DNA or histone molecules, interactions … insights into the patterns
of epigenetic alterations essential in … MiRNA are known to regulate the stem cell properties by …