Targeting growth hormone function: strategies and therapeutic applications

M Lu, JU Flanagan, RJ Langley, MP Hay… - Signal transduction and …, 2019 - nature.com
growth hormone (GH) is a peptide hormone that is secreted from the anterior pituitary. It has
a central function of regulating postnatal growth and metabolism … increasingly complex GH …

Growth hormone (s), testosterone, insulin-like growth factors, and cortisol: roles and integration for cellular development and growth with exercise

WJ Kraemer, NA Ratamess, WC Hymer… - Frontiers in …, 2020 - frontiersin.org
… As a direct target gene of the glucocorticoid receptor with a diurnal response pattern,
KLF15 signaling may explain the complex role of glucocorticoids in metabolism and protein …

The effects of growth hormone on adipose tissue: old observations, new mechanisms

JJ Kopchick, DE Berryman, V Puri, KY Lee… - Nature Reviews …, 2020 - nature.com
… The ability of growth hormone (GH) to induce adipose tissue … has evolved to reveal a
complex structure with distinct types … a physiological role of GH to partition substrate metabolism

The role of thyroid hormone in metabolism and metabolic syndrome

PFS Teixeira, PB Dos Santos… - … and metabolism, 2020 - journals.sagepub.com
… For this purpose, we did not include a detailed analysis of studies focusing on the effect
of bariatric surgery on thyroid, even though a recent meta-analysis found that patients who …

New findings on brain actions of growth hormone and potential clinical implications

J Donato Jr, JJ Kopchick - Reviews in Endocrine and Metabolic Disorders, 2024 - Springer
… GH secretion presents a complex pattern characterized by pulses interspersed with periods
… of greatest body growth, highlighting the critical role of this hormone in somatic growth. …

The role of growth hormone on ovarian functioning and ovarian angiogenesis

J Devesa, D Caicedo - Frontiers in endocrinology, 2019 - frontiersin.org
… to a pituitary dwarf (1), the pituitary growth hormone (GH) has been considered a metabolic
… In summary, the onset of puberty in girls is a very complex process in which many factors …

Growth hormone deficiency: health and longevity

MH Aguiar-Oliveira, A Bartke - Endocrine reviews, 2019 - academic.oup.com
… indicate that actions of GH on growth, maturation, and metabolism involve significant costs
in terms of aging and longevity Novel information about the role of GH in human aging was …

Vitamin D and growth hormone in children: a review of the current scientific knowledge

S Esposito, A Leonardi, L Lanciotti, M Cofini… - Journal of Translational …, 2019 - Springer
… glucose uptake both in muscles and in the liver to change metabolism to lipid utilization [40]. …
complex functions catalyzes the 25-hydroxylation of vitamin D in hepatoblastoma cells [51]. …

Growth hormone and insulin-like growth factor action in reproductive tissues

E Ipsa, VF Cruzat, JN Kagize, JL Yovich… - Frontiers in …, 2019 - frontiersin.org
… and development via action on key metabolic organs including the liver, skeletal muscle, …
-STAT signaling events which has multiple complex roles, such as regulating cell proliferation …

[PDF][PDF] Growth hormone and aging: updated review

A Bartke - The World Journal of Men's Health, 2019 - synapse.koreamed.org
… diol 17 beta, testosterone, or growth hormone (GH) can be viewed as … In this article, we will
provide an overview of the intricategrowth hormone on body composition and metabolism in …