Role of gangliosides in peripheral pain mechanisms
P Sántha, I Dobos, G Kis, G Jancsó - International Journal of Molecular …, 2020 - mdpi.com
… Different classes of gangliosides are expressed in nociceptive primary sensory neurons
involved … An antinociceptive effect of intrathecally administered ganglioside GM1 has also been …
involved … An antinociceptive effect of intrathecally administered ganglioside GM1 has also been …
Curcumin induces peripheral antinociception by opioidergic and cannabinoidergic mechanism: Pharmacological evidence
DD Aguiar, ACR Gonzaga, ALH Teófilo, FA Miranda… - Life Sciences, 2022 - Elsevier
… of researches demonstrating the analgesic potential of … systems participate in the peripheral
antinociception induced by … COX-2), lipoxygenase and induction of nitric oxide synthase. The …
antinociception induced by … COX-2), lipoxygenase and induction of nitric oxide synthase. The …
Systemic and peripheral mechanisms of cortical stimulation-induced analgesia and refractoriness in a rat model of neuropathic pain
DV Assis, ACP Campos, AFN Paschoa… - International journal of …, 2023 - mdpi.com
… involved in persistent pain [16,41], in the neuronal bodies cluster found in the DRG. Two …
of SP, suggesting that antinociception or refractoriness is not directly linked to SP levels. In …
of SP, suggesting that antinociception or refractoriness is not directly linked to SP levels. In …
Nitric oxide and opioids involvement in isobolographic NSAIDs antinociception
HF Miranda, V Noriega, F Sierralta, P Poblete… - Drug …, 2019 - thieme-connect.com
… Different NSAIDs are used as antinociceptive in various analgesic assays, among which
should … in the central nervous system synthetized by the enzymes nitric oxide synthase (NOS). …
should … in the central nervous system synthetized by the enzymes nitric oxide synthase (NOS). …
[HTML][HTML] Non-opioid analgesics and the endocannabinoid system
RD Topuz, Ö Gündüz, ÇH Karadağ… - Balkan medical …, 2020 - ncbi.nlm.nih.gov
… inhibition of nitric oxide synthase production, and induction of … participate in the antinociceptive
effects of analgesic drugs. … the target of many therapies, as it is involved in a number of …
effects of analgesic drugs. … the target of many therapies, as it is involved in a number of …
Peripheral antinociception induced by ketamine is mediated by the endogenous opioid system
JA Petrocchi, DL de Almeida, P Paiva-Lima… - European journal of …, 2019 - Elsevier
… in the mechanism of peripheral analgesia induced by ketamine… neuronal nitric oxide synthase
(nNOS) enzyme to produce … ketamine might be participating in the synthesis and release of …
(nNOS) enzyme to produce … ketamine might be participating in the synthesis and release of …
Bupleurum falcatum L. alleviates nociceptive and neuropathic pain: Potential mechanisms of action
D Ahmadimoghaddam, M Zarei, S Mohammadi… - Journal of …, 2021 - Elsevier
… (BFEO)-induced peripheral antinociception during the early … mechanism(s) involved in the
antinociceptive effects of BFEO. … of NO via local activation of nitric oxide synthase (NOS). The …
antinociceptive effects of BFEO. … of NO via local activation of nitric oxide synthase (NOS). The …
Hyperbaric oxygen produces a nitric oxide synthase-regulated anti-allodynic effect in rats with paclitaxel-induced neuropathic pain
Y Zhang, AL Brewer, JT Nelson, PT Smith, DY Shirachi… - Brain research, 2019 - Elsevier
… ascertain whether HBO 2 -induced antinociception in a chronic … Many patients do not achieve
satisfactory pain relief with … the supraspinal involvement of NOS activity and NO production …
satisfactory pain relief with … the supraspinal involvement of NOS activity and NO production …
Involvement of NO in antinociception of NSAIDS in murine formalin hind paw assay
V Noriega, HF Miranda, JC Prieto… - Drug …, 2020 - thieme-connect.com
… NAME or 7-nitroindazol induced a significant increase of the analgesic power of the NSAIDs…
of nitric oxide synthase (NOS). Three different forms of NOS have been identified: neuronal …
of nitric oxide synthase (NOS). Three different forms of NOS have been identified: neuronal …
Analgesic effect of acetaminophen: a review of known and novel mechanisms of action
N Ohashi, T Kohno - Frontiers in Pharmacology, 2020 - frontiersin.org
… the most commonly used analgesic agents for treating acute … has several subtypes, and
acetaminophen-induced analgesia … These findings implied that acetaminophen may be involved …
acetaminophen-induced analgesia … These findings implied that acetaminophen may be involved …