Endoglin: beyond the endothelium

MJA Schoonderwoerd, MJTH Goumans… - Biomolecules, 2020 - mdpi.com
role of endoglin in innate and adaptive immunity. Finally, we will discuss the results of clinical
trials using the endoglin … and subsequently released into the circulation system. This might …

Membrane and soluble endoglin role in cardiovascular and metabolic disorders related to metabolic syndrome

M Vicen, IC Igreja Sá, K Tripská, B Vitverová… - Cellular and Molecular …, 2021 - Springer
… idiopathic or hereditary PAH, PAH associated with connective tissue disease, drug, or
toxin-related PAH, but not with PAH related to congenital heart disease [17]. Also, Coral-Alvarado …

[HTML][HTML] Novel vascular roles of human endoglin in pathophysiology

E Rossi, C Bernabeu - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
… Basal endoglin expression levels vary in the vascular endothelium of different tissues,
whereas they are clearly upregulated in ECs from inflamed tissues with an associated …

Endoglin/CD105-based imaging of cancer and cardiovascular diseases: a systematic review

VQ Sier, JR van der Vorst, PHA Quax… - International journal of …, 2021 - mdpi.com
… 64 Cu-NOTA-TRC105-(Fab) has been employed in three different cardiovascular disease
models to achieve endoglin-based PET imaging: murine hindlimb ischemia, rat myocardial …

Dynamic changes in endoglin expression in the developing mouse heart

E Singh, HM Phillips, HM Arthur - Gene Expression Patterns, 2021 - Elsevier
Endoglin (ENG) is essential for cardiovascular development and is expressed in the heart
ENG expression has been reported in the cardiac crescent, endocardium, valve mesenchyme …

Endoglin as an adhesion molecule in mature and progenitor endothelial cells: a function beyond TGF-β

E Rossi, C Bernabeu, DM Smadja - Frontiers in medicine, 2019 - frontiersin.org
… cell types present in the circulatory system have also revealed … the role of endoglin in ECs,
it is worth mentioning that endoglin … However, a review on the endoglin role in these cell types …

Potential role of circulating endoglin in hypertension via the upregulated expression of BMP4

E Gallardo-Vara, L Gamella-Pozuelo, L Perez-Roque… - Cells, 2020 - mdpi.com
… defects, suggesting a key role of endoglin in the vascular system [11]. Endoglin is a 180-kDa …
The juxtamembrane region of the endoglin ectodomain can be proteolytically targeted by …

Investigating the roles of endoglin in cardiovascular development, disease and repair

RO Snodgrass - 2022 - etheses.whiterose.ac.uk
… of endoglin’s role in cardiovascular diseases such as MI and HHT. My project investigates
the role of endoglin in vascular development and diseaseThe vascular system supplies cells …

The role of endoglin and its soluble form in pathogenesis of preeclampsia

G Margioula-Siarkou, C Margioula-Siarkou… - Molecular and Cellular …, 2022 - Springer
… On the contrary, there are various distinct mechanisms which promote the cleavage of the
extracellular domain from membrane endoglin, releasing soluble endoglin in circulation to …

Endoglin: An 'accessory'receptor regulating blood cell development and inflammation

SK Meurer, R Weiskirchen - International Journal of Molecular Sciences, 2020 - mdpi.com
… However, one of the characteristic signs of HHT is recurrent nosebleeds, which have
been assigned to defects in the vascular system [113]. However, the coagulation time and …