The role of epigenetics in placental development and the etiology of preeclampsia

C Apicella, CSM Ruano, C Méhats, F Miralles… - International journal of …, 2019 - mdpi.com
… The placenta is a temporary organ connecting the developing fetus to the uterine wall … That
was explained by rapid and transient repression of genes at the time of SCT formation. SCTs …

Preeclampsia is a syndrome with a cascade of pathophysiologic events

W Gyselaers - Journal of clinical medicine, 2020 - mdpi.com
… of placental tissue confirmed greater placental … or more organs. Together, the information
summarized in this review demonstrates that PE is not a unicausal disorder but a multifaceted, …

Author Spotlight: Advancing Research Through Single Cell Sequencing and Spatial Histology in Placental Tissues

N Kupper, E Pritz, M Siwetz, J Guettler… - JoVE (Journal of …, 2023 - jove.com
… , where the placenta encounters constant slight … placental explant cultivation closer to the
in utero flow conditions experienced within the maternal body. Within this approach, placental

Placental proteins with predicted roles in fetal development decrease in premature infants

C Schreiner, TL Powell, C Palmer, T Jansson - Pediatric research, 2022 - nature.com
… The late second trimester human placenta secretes proteins into the fetal circulation which
… of fetal organs. Further studies are needed to directly link placental proteins to organ

Maternal dexamethasone exposure induces sex-specific changes in histomorphology and redox homeostasis of rat placenta

S Trifunović, B Šošić Jurjević, N Ristić… - International Journal of …, 2022 - mdpi.com
… The placenta is a temporary organ, acting during gestation as the primary exchange line for
nutrients, gas, waste and communication between mother and fetus [1]. The chorioallantoic …

[HTML][HTML] The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system

N Kupper, B Huppertz - Molecular Aspects of Medicine, 2022 - Elsevier
… During its transient existence, the fetus is entirely dependent on the placenta since it acts
as the … As a fetal organ, the mature placenta has mostly fetal aspects, but contains maternal …

Nanoparticles at the maternal-fetal interface

S Adams, PA Stapleton - Molecular and Cellular Endocrinology, 2023 - Elsevier
… The placenta is a transient, temporary organ of fetal origin … is to highlight the placenta as
an endocrine organ, describe the … Environmental NP are often multi-faceted, often containing …

Ablation of placental REST deregulates fetal brain metabolism and impacts gene expression of the offspring brain at the postnatal and adult stages

M Islam, A Samal, DJ Davis, SK Behura - The FASEB Journal, 2024 - Wiley Online Library
In this study, the transcriptional repressor REST (Repressor Element 1 Silencing Transcription
factor) was ablated in the mouse placenta to investigate molecular and cellular impacts on …

[PDF][PDF] Progress in deciphering trophoblast cell differentiation during human placentation

X Zhenyu, L Xiaoyan - 2020 - 159.226.67.71
… The human placenta, a vivipara-associated endocrine organ, … essential yet least understood
foetal organ for the successful … -lethal mice showed disordered placental development. This …

[HTML][HTML] Maternal and intrauterine influences on feto-placental growth are accompanied by sexually dimorphic changes in placental mitochondrial respiration, and …

E Salazar-Petres, D Pereira-Carvalho, J Lopez-Tello… - Cells, 2023 - mdpi.com
… and transcriptomic analyses of mouse placental LZ and human placental villous samples
showed that over 80% of genes implicated in mouse placental phenotypes are co-expressed in …