Transient receptor potential vanilloid 1 (TRPV1)‐independent actions of capsaicin on cellular excitability and ion transport
… a non-pungent TRPV1 agonist in DRG neurons. … Capsaicin (1–100 µM) Wistar rat trigeminal
ganglia and hippocampal pyramidal neurons/patch-clamp technique Direct inhibition of Ca 2…
ganglia and hippocampal pyramidal neurons/patch-clamp technique Direct inhibition of Ca 2…
Discovery of nonpungent transient receptor potential vanilloid 1 (TRPV1) agonist as strong topical analgesic
… the pattern of response. In our program to develop a nonpungent, highly efficacious TRPV1
agonist to avoid the adverse effects associated with the use of capsaicin, we investigated a …
agonist to avoid the adverse effects associated with the use of capsaicin, we investigated a …
[HTML][HTML] Co-application of eugenol and QX-314 elicits the prolonged blockade of voltage-gated sodium channels in nociceptive trigeminal ganglion neurons
… -heat-sensitive transient receptor potential vanilloid 1 (TRPV1) … manner in capsaicin-sensitive
TG neurons. Eugenol also … using nonpungent agonists of TRPV1 other than capsaicin is …
TG neurons. Eugenol also … using nonpungent agonists of TRPV1 other than capsaicin is …
The desensitization of the transient receptor potential vanilloid 1 by nonpungent agonists and its resensitization by bradykinin
… as capsaicin [ 2 , 3 ], as well as nonpungent capsaicin-… 2 (not B 1 ) receptors potentially
induce the synthesis of prostaglandins in adult rat trigeminal ganglia cultures and in isolated rat …
induce the synthesis of prostaglandins in adult rat trigeminal ganglia cultures and in isolated rat …
[HTML][HTML] Endogenous and Exogenous Vanilloids Evoke Disparate TRPV1 Activation to Produce Distinct Neuronal Responses
… Here, we sought to describe the neuronal response of TRPV1… in rat trigeminal neurons
exposed to either capsaicin or … -diameter dissociated rat trigeminal ganglion (TG) neurons (P0) …
exposed to either capsaicin or … -diameter dissociated rat trigeminal ganglion (TG) neurons (P0) …
[HTML][HTML] Beyond neuronal heat sensing: diversity of TRPV1 heat-capsaicin receptor-channel functions
YM Shuba - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
… , capsaicin, and related chemicals from the group of vanilloids as well as by noxious heat. As
such, it is mostly expressed in sensory neurons … ) and non-pungent (capsinoids) capsaicin-…
such, it is mostly expressed in sensory neurons … ) and non-pungent (capsinoids) capsaicin-…
[HTML][HTML] Pungency perception and the interaction with basic taste sensations: an overview
W He, L Liang, Y Zhang - Foods, 2023 - mdpi.com
… transduced through transient receptor potential vanilloid 1 (TRPV1) … trigeminal nerve elicited
by substances, such as capsaicin, … The effect of salivary secretion in response to capsaicin …
by substances, such as capsaicin, … The effect of salivary secretion in response to capsaicin …
[HTML][HTML] Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain
… Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1), which is
… We will further classify defunctionalization into two types based on capsaicin dose, duration, …
… We will further classify defunctionalization into two types based on capsaicin dose, duration, …
[HTML][HTML] Interactions between chemesthesis and taste: role of TRPA1 and TRPV1
MR Rhyu, Y Kim, V Lyall - International journal of molecular sciences, 2021 - mdpi.com
… often co-expressed in trigeminal ganglion neurons, and are the most … The effects of capsaicin
are also mimicked by its non-pungent … vanilloid 1 (TRPV1) monomer. The vanillyl moiety of …
are also mimicked by its non-pungent … vanilloid 1 (TRPV1) monomer. The vanillyl moiety of …
Natural products and some semi-synthetic analogues as potential TRPV1 ligands for attenuating neuropathic pain
GG Naik, A Uniyal, D Chouhan… - Current …, 2022 - ingentaconnect.com
… [3H]-RTX binding sites, particularly in rat trigeminal ganglion, … of the responses mediated via
capsaicin in DRG neurons as well … of vanilloid agonists at the recombinant rat vanilloid VR1 …
capsaicin in DRG neurons as well … of vanilloid agonists at the recombinant rat vanilloid VR1 …